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Cyclic bridged analogs of isoCA-4: Design, synthesis and biological evaluation.
Pecnard S, Provot O, Levaique H, Bignon J, Askenatzis L, Saller F, Borgel D, Michallet S, Laisne MC, Lafanechère L, Alami M, Hamze A. Pecnard S, et al. Among authors: askenatzis l. Eur J Med Chem. 2021 Jan 1;209:112873. doi: 10.1016/j.ejmech.2020.112873. Epub 2020 Oct 4. Eur J Med Chem. 2021. PMID: 33038796
Design, synthesis and biological evaluation of quinoline-2-carbonitrile-based hydroxamic acids as dual tubulin polymerization and histone deacetylases inhibitors.
Hauguel C, Ducellier S, Provot O, Ibrahim N, Lamaa D, Balcerowiak C, Letribot B, Nascimento M, Blanchard V, Askenatzis L, Levaique H, Bignon J, Baschieri F, Bauvais C, Bollot G, Renko D, Deroussent A, Prost B, Laisne MC, Michallet S, Lafanechère L, Papot S, Montagnac G, Tran C, Alami M, Apcher S, Hamze A. Hauguel C, et al. Among authors: askenatzis l. Eur J Med Chem. 2022 Oct 5;240:114573. doi: 10.1016/j.ejmech.2022.114573. Epub 2022 Jul 1. Eur J Med Chem. 2022. PMID: 35797900 Free article.
Structure-Based Design of a Lead Compound Derived from Natural Schweinfurthins with Antitumor Properties That Target Oxysterol-Binding Protein.
Jézéquel G, Rampal C, Guimard C, Kovacs D, Polidori J, Bigay J, Bignon J, Askenatzis L, Litaudon M, Pham VC, Huong DTM, Nguyen AL, Pruvost A, Virolle T, Mesmin B, Desrat S, Antonny B, Roussi F. Jézéquel G, et al. Among authors: askenatzis l. J Med Chem. 2023 Oct 26;66(20):14208-14220. doi: 10.1021/acs.jmedchem.3c01298. Epub 2023 Oct 5. J Med Chem. 2023. PMID: 37795600