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A reverse translational approach reveals the protective roles of Mangifera indica in inflammatory bowel disease.
Saviano A, Schettino A, Iaccarino N, Mansour AA, Begum J, Marigliano N, Raucci F, Romano F, Riccardi G, Mitidieri E, d'Emmanuele di Villa Bianca R, Bello I, Panza E, Smimmo M, Vellecco V, Rimmer P, Cheesbrough J, Zhi Z, Iqbal TH, Pieretti S, D'Amore VM, Marinelli L, La Pietra V, Sorrentino R, Costa L, Caso F, Scarpa R, Cirino G, Randazzo A, Bucci M, McGettrick HM, Iqbal AJ, Maione F. Saviano A, et al. Among authors: iqbal aj. J Autoimmun. 2024 Apr;144:103181. doi: 10.1016/j.jaut.2024.103181. Epub 2024 Mar 23. J Autoimmun. 2024. PMID: 38522129
Activation of GPBAR1 attenuates vascular inflammation and atherosclerosis in a mouse model of NAFLD-related cardiovascular disease.
Biagioli M, Marchianò S, Di Giorgio C, Bordoni M, Urbani G, Bellini R, Massa C, Sami Ullah Khan R, Roselli R, Chiara Monti M, Morretta E, Giordano A, Vellecco V, Bucci M, Jilani Iqbal A, Saviano A, Ab Mansour A, Ricci P, Distrutti E, Zampella A, Cieri E, Cirino G, Fiorucci S. Biagioli M, et al. Among authors: jilani iqbal a. Biochem Pharmacol. 2023 Dec;218:115900. doi: 10.1016/j.bcp.2023.115900. Epub 2023 Nov 3. Biochem Pharmacol. 2023. PMID: 37926268 Free article.
New biologic (Ab-IPL-IL-17) for IL-17-mediated diseases: identification of the bioactive sequence (nIL-17) for IL-17A/F function.
Saviano A, Manosour AA, Raucci F, Merlino F, Marigliano N, Schettino A, Wahid M, Begum J, Filer A, Manning JE, Casillo GM, Piccolo M, Ferraro MG, Marzano S, Russomanno P, Bellavita R, Irace C, Amato J, Alfaifi M, Rimmer P, Iqbal T, Pieretti S, Vellecco V, Caso F, Costa L, Giacomelli R, Scarpa R, Cirino G, Bucci M, McGettrick HM, Grieco P, Iqbal AJ, Maione F. Saviano A, et al. Among authors: iqbal aj. Ann Rheum Dis. 2023 Nov;82(11):1415-1428. doi: 10.1136/ard-2023-224479. Epub 2023 Aug 14. Ann Rheum Dis. 2023. PMID: 37580108 Free PMC article.
Interleukin-17 (IL-17) triggers systemic inflammation, peripheral vascular dysfunction, and related prothrombotic state in a mouse model of Alzheimer's disease.
Vellecco V, Saviano A, Raucci F, Casillo GM, Mansour AA, Panza E, Mitidieri E, Femminella GD, Ferrara N, Cirino G, Sorrentino R, Iqbal AJ, d'Emmanuele di Villa Bianca R, Bucci M, Maione F. Vellecco V, et al. Among authors: iqbal aj. Pharmacol Res. 2023 Jan;187:106595. doi: 10.1016/j.phrs.2022.106595. Epub 2022 Dec 5. Pharmacol Res. 2023. PMID: 36470548 Free article.
Anti-inflammatory and immunomodulatory activity of Mangifera indica L. reveals the modulation of COX-2/mPGES-1 axis and Th17/Treg ratio.
Saviano A, Raucci F, Casillo GM, Mansour AA, Piccolo V, Montesano C, Smimmo M, Vellecco V, Capasso G, Boscaino A, Summa V, Mascolo N, Iqbal AJ, Sorrentino R, d'Emmanuele di Villa Bianca R, Bucci M, Brancaleone V, Maione F. Saviano A, et al. Among authors: iqbal aj. Pharmacol Res. 2022 Aug;182:106283. doi: 10.1016/j.phrs.2022.106283. Epub 2022 Jun 1. Pharmacol Res. 2022. PMID: 35662629
IL-17-induced inflammation modulates the mPGES-1/PPAR-γ pathway in monocytes/macrophages.
Raucci F, Saviano A, Casillo GM, Guerra-Rodriguez M, Mansour AA, Piccolo M, Ferraro MG, Panza E, Vellecco V, Irace C, Caso F, Scarpa R, Mascolo N, Alfaifi M, Iqbal AJ, Maione F. Raucci F, et al. Among authors: iqbal aj. Br J Pharmacol. 2022 May;179(9):1857-1873. doi: 10.1111/bph.15413. Epub 2021 Mar 21. Br J Pharmacol. 2022. PMID: 33595097 Free article.
Present Status and Future Trends of Natural-Derived Compounds Targeting T Helper (Th) 17 and Microsomal Prostaglandin E Synthase-1 (mPGES-1) as Alternative Therapies for Autoimmune and Inflammatory-Based Diseases.
Saviano A, Raucci F, Casillo GM, Indolfi C, Pernice A, Foreste C, Iqbal AJ, Mascolo N, Maione F. Saviano A, et al. Among authors: iqbal aj. Molecules. 2020 Dec 18;25(24):6016. doi: 10.3390/molecules25246016. Molecules. 2020. PMID: 33353211 Free PMC article. Review.
20 results