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Harmonizing Biopredictive Methodologies Through the Product Quality Research Institute (PQRI) Part I: Biopredictive Dissolution of Ibuprofen and Dipyridamole Tablets.
Tsume Y, Ashworth L, Bermejo M, Cheng J, Cicale V, Dressman J, Fushimi M, Gonzalez-Alvarez I, Guo Y, Jankovsky C, Lu X, Matsui K, Patel S, Sanderson N, Sun CC, Thakral NK, Yamane M, Zöller L. Tsume Y, et al. Among authors: ashworth l. AAPS J. 2023 Apr 21;25(3):45. doi: 10.1208/s12248-023-00793-7. AAPS J. 2023. PMID: 37085637
An investigation into the utility of a multi-compartmental, dynamic, system of the upper gastrointestinal tract to support formulation development and establish bioequivalence of poorly soluble drugs.
Dickinson PA, Abu Rmaileh R, Ashworth L, Barker RA, Burke WM, Patterson CM, Stainforth N, Yasin M. Dickinson PA, et al. Among authors: ashworth l. AAPS J. 2012 Jun;14(2):196-205. doi: 10.1208/s12248-012-9333-x. Epub 2012 Feb 29. AAPS J. 2012. PMID: 22374384 Free PMC article. Clinical Trial.
Validation of Dissolution Testing with Biorelevant Media: An OrBiTo Study.
Mann J, Dressman J, Rosenblatt K, Ashworth L, Muenster U, Frank K, Hutchins P, Williams J, Klumpp L, Wielockx K, Berben P, Augustijns P, Holm R, Hofmann M, Patel S, Beato S, Ojala K, Tomaszewska I, Bruel JL, Butler J. Mann J, et al. Among authors: ashworth l. Mol Pharm. 2017 Dec 4;14(12):4192-4201. doi: 10.1021/acs.molpharmaceut.7b00198. Epub 2017 Aug 23. Mol Pharm. 2017. PMID: 28737403
Biorelevant dissolution testing of a weak base: Interlaboratory reproducibility and investigation of parameters controlling in vitro precipitation.
Berben P, Ashworth L, Beato S, Bevernage J, Bruel JL, Butler J, Dressman J, Schäfer K, Hutchins P, Klumpp L, Mann J, Nicolai J, Ojala K, Patel S, Powell S, Rosenblatt K, Tomaszewska I, Williams J, Augustijns P. Berben P, et al. Among authors: ashworth l. Eur J Pharm Biopharm. 2019 Jul;140:141-148. doi: 10.1016/j.ejpb.2019.04.017. Epub 2019 Apr 30. Eur J Pharm Biopharm. 2019. PMID: 31051249
Correction: Harmonizing Biopredictive Methodologies Through the Product Quality Research Institute (PQRI) Part I: Biopredictive Dissolution of Ibuprofen and Dipyridamole Tablets.
Tsume Y, Ashworth L, Bermejo M, Cheng J, Cicale V, Dressman J, Fushimi M, Gonzalez-Alvarez I, Guo Y, Jankovsky C, Lu X, Matsui K, Patel S, Sanderson N, Sun CC, Thakral NK, Yamane M, Zöller L. Tsume Y, et al. Among authors: ashworth l. AAPS J. 2023 Jun 8;25(4):58. doi: 10.1208/s12248-023-00827-0. AAPS J. 2023. PMID: 37291273 No abstract available.
Ecological interactions affect the bioactivity of medicinal plants.
Camina JL, Usseglio V, Marquez V, Merlo C, Dambolena JS, Zygadlo JA, Ashworth L. Camina JL, et al. Among authors: ashworth l. Sci Rep. 2023 Jul 27;13(1):12165. doi: 10.1038/s41598-023-39358-1. Sci Rep. 2023. PMID: 37500739 Free PMC article.
Safety and efficacy of rozanolixizumab in patients with generalised myasthenia gravis (MycarinG): a randomised, double-blind, placebo-controlled, adaptive phase 3 study.
Bril V, Drużdż A, Grosskreutz J, Habib AA, Mantegazza R, Sacconi S, Utsugisawa K, Vissing J, Vu T, Boehnlein M, Bozorg A, Gayfieva M, Greve B, Woltering F, Kaminski HJ; MG0003 study team. Bril V, et al. Lancet Neurol. 2023 May;22(5):383-394. doi: 10.1016/S1474-4422(23)00077-7. Lancet Neurol. 2023. PMID: 37059507 Clinical Trial.
198 results