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The DNA damage response and cancer therapy.
Lord CJ, Ashworth A. Lord CJ, et al. Among authors: ashworth a. Nature. 2012 Jan 18;481(7381):287-94. doi: 10.1038/nature10760. Nature. 2012. PMID: 22258607 Review.
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy.
Farmer H, McCabe N, Lord CJ, Tutt AN, Johnson DA, Richardson TB, Santarosa M, Dillon KJ, Hickson I, Knights C, Martin NM, Jackson SP, Smith GC, Ashworth A. Farmer H, et al. Among authors: ashworth a. Nature. 2005 Apr 14;434(7035):917-21. doi: 10.1038/nature03445. Nature. 2005. PMID: 15829967 Free article.
Functional analysis of Drosophila melanogaster BRCA2 in DNA repair.
Brough R, Wei D, Leulier S, Lord CJ, Rong YS, Ashworth A. Brough R, et al. Among authors: ashworth a. DNA Repair (Amst). 2008 Jan 1;7(1):10-9. doi: 10.1016/j.dnarep.2007.07.013. Epub 2007 Sep 5. DNA Repair (Amst). 2008. PMID: 17822964
Resistance to therapy caused by intragenic deletion in BRCA2.
Edwards SL, Brough R, Lord CJ, Natrajan R, Vatcheva R, Levine DA, Boyd J, Reis-Filho JS, Ashworth A. Edwards SL, et al. Among authors: ashworth a. Nature. 2008 Feb 28;451(7182):1111-5. doi: 10.1038/nature06548. Epub 2008 Feb 10. Nature. 2008. PMID: 18264088
DNA repair deficiency as a therapeutic target in cancer.
Martin SA, Lord CJ, Ashworth A. Martin SA, et al. Among authors: ashworth a. Curr Opin Genet Dev. 2008 Feb;18(1):80-6. doi: 10.1016/j.gde.2008.01.016. Epub 2008 Mar 14. Curr Opin Genet Dev. 2008. PMID: 18343102 Review.
822 results