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'In-Format' screening of a novel bispecific antibody format reveals significant potency improvements relative to unformatted molecules.
MAbs. 2017 Jan;9(1):85-93. doi: 10.1080/19420862.2016.1249078. Epub 2016 Oct 27.
MAbs. 2017.
PMID: 27786601
Free PMC article.
Efficacy and safety of an anti-IL-13 mAb in patients with severe asthma: a randomized trial.
De Boever EH, Ashman C, Cahn AP, Locantore NW, Overend P, Pouliquen IJ, Serone AP, Wright TJ, Jenkins MM, Panesar IS, Thiagarajah SS, Wenzel SE.
De Boever EH, et al.
J Allergy Clin Immunol. 2014 Apr;133(4):989-96. doi: 10.1016/j.jaci.2014.01.002. Epub 2014 Feb 28.
J Allergy Clin Immunol. 2014.
PMID: 24582316
Clinical Trial.
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A phase 1, randomized, placebo-controlled, dose-escalation study of an anti-IL-13 monoclonal antibody in healthy subjects and mild asthmatics.
Hodsman P, Ashman C, Cahn A, De Boever E, Locantore N, Serone A, Pouliquen I.
Hodsman P, et al.
Br J Clin Pharmacol. 2013 Jan;75(1):118-28. doi: 10.1111/j.1365-2125.2012.04334.x.
Br J Clin Pharmacol. 2013.
PMID: 22616628
Free PMC article.
Clinical Trial.
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