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Management of glioblastoma: State of the art and future directions.
Tan AC, Ashley DM, López GY, Malinzak M, Friedman HS, Khasraw M. Tan AC, et al. Among authors: ashley dm. CA Cancer J Clin. 2020 Jul;70(4):299-312. doi: 10.3322/caac.21613. Epub 2020 Jun 1. CA Cancer J Clin. 2020. PMID: 32478924 Free article. Review.
Salting the Soil: Targeting the Microenvironment of Brain Metastases.
Srinivasan ES, Tan AC, Anders CK, Pendergast AM, Sipkins DA, Ashley DM, Fecci PE, Khasraw M. Srinivasan ES, et al. Among authors: ashley dm. Mol Cancer Ther. 2021 Mar;20(3):455-466. doi: 10.1158/1535-7163.MCT-20-0579. Epub 2021 Jan 5. Mol Cancer Ther. 2021. PMID: 33402399 Free PMC article. Review.
Very low mutation burden is a feature of inflamed recurrent glioblastomas responsive to cancer immunotherapy.
Gromeier M, Brown MC, Zhang G, Lin X, Chen Y, Wei Z, Beaubier N, Yan H, He Y, Desjardins A, Herndon JE 2nd, Varn FS, Verhaak RG, Zhao J, Bolognesi DP, Friedman AH, Friedman HS, McSherry F, Muscat AM, Lipp ES, Nair SK, Khasraw M, Peters KB, Randazzo D, Sampson JH, McLendon RE, Bigner DD, Ashley DM. Gromeier M, et al. Among authors: ashley dm. Nat Commun. 2021 Jan 13;12(1):352. doi: 10.1038/s41467-020-20469-6. Nat Commun. 2021. PMID: 33441554 Free PMC article.
A randomized phase II trial of veliparib, radiotherapy, and temozolomide in patients with unmethylated MGMT glioblastoma: the VERTU study.
Sim HW, McDonald KL, Lwin Z, Barnes EH, Rosenthal M, Foote MC, Koh ES, Back M, Wheeler H, Sulman EP, Buckland ME, Fisher L, Leonard R, Hall M, Ashley DM, Yip S, Simes J, Khasraw M. Sim HW, et al. Among authors: ashley dm. Neuro Oncol. 2021 Oct 1;23(10):1736-1749. doi: 10.1093/neuonc/noab111. Neuro Oncol. 2021. PMID: 33984151 Free PMC article. Clinical Trial.
Systematic review of combinations of targeted or immunotherapy in advanced solid tumors.
Tan AC, Bagley SJ, Wen PY, Lim M, Platten M, Colman H, Ashley DM, Wick W, Chang SM, Galanis E, Mansouri A, Khagi S, Mehta MP, Heimberger AB, Puduvalli VK, Reardon DA, Sahebjam S, Simes J, Antonia SJ, Berry D, Khasraw M. Tan AC, et al. Among authors: ashley dm. J Immunother Cancer. 2021 Jul;9(7):e002459. doi: 10.1136/jitc-2021-002459. J Immunother Cancer. 2021. PMID: 34215688 Free PMC article. Review.
Designing Clinical Trials for Combination Immunotherapy: A Framework for Glioblastoma.
Singh K, Batich KA, Wen PY, Tan AC, Bagley SJ, Lim M, Platten M, Colman H, Ashley DM, Chang SM, Rahman R, Galanis E, Mansouri A, Puduvalli VK, Reardon DA, Sahebjam S, Sampson JH, Simes J, Berry DA, Zadeh G, Cloughesy TF, Mehta MP, Piantadosi S, Weller M, Heimberger AB, Khasraw M. Singh K, et al. Among authors: ashley dm. Clin Cancer Res. 2022 Feb 15;28(4):585-593. doi: 10.1158/1078-0432.CCR-21-2681. Clin Cancer Res. 2022. PMID: 34561270 Free PMC article. Review.
Low tumor mutational burden and immunotherapy in gliomas.
Brown MC, Ashley DM, Khasraw M. Brown MC, et al. Among authors: ashley dm. Trends Cancer. 2022 May;8(5):345-346. doi: 10.1016/j.trecan.2022.01.006. Epub 2022 Jan 31. Trends Cancer. 2022. PMID: 35093301 No abstract available.
Glioma progression is shaped by genetic evolution and microenvironment interactions.
Varn FS, Johnson KC, Martinek J, Huse JT, Nasrallah MP, Wesseling P, Cooper LAD, Malta TM, Wade TE, Sabedot TS, Brat D, Gould PV, Wöehrer A, Aldape K, Ismail A, Sivajothi SK, Barthel FP, Kim H, Kocakavuk E, Ahmed N, White K, Datta I, Moon HE, Pollock S, Goldfarb C, Lee GH, Garofano L, Anderson KJ, Nehar-Belaid D, Barnholtz-Sloan JS, Bakas S, Byrne AT, D'Angelo F, Gan HK, Khasraw M, Migliozzi S, Ormond DR, Paek SH, Van Meir EG, Walenkamp AME, Watts C, Weiss T, Weller M, Palucka K, Stead LF, Poisson LM, Noushmehr H, Iavarone A, Verhaak RGW; GLASS Consortium. Varn FS, et al. Cell. 2022 Jun 9;185(12):2184-2199.e16. doi: 10.1016/j.cell.2022.04.038. Epub 2022 May 31. Cell. 2022. PMID: 35649412 Free PMC article.
The role of chemotherapy in the treatment of central neurocytoma.
Johnson MO, Kirkpatrick JP, Patel MP, Desjardins A, Randazzo DM, Friedman HS, Ashley DM, Peters KB. Johnson MO, et al. Among authors: ashley dm. CNS Oncol. 2019 Nov 1;8(3):CNS41. doi: 10.2217/cns-2019-0012. Epub 2019 Nov 5. CNS Oncol. 2019. PMID: 31686534 Free PMC article. Review.
169 results