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Reducing the RNA binding protein TIA1 protects against tau-mediated neurodegeneration in vivo.
Apicco DJ, Ash PEA, Maziuk B, LeBlang C, Medalla M, Al Abdullatif A, Ferragud A, Botelho E, Ballance HI, Dhawan U, Boudeau S, Cruz AL, Kashy D, Wong A, Goldberg LR, Yazdani N, Zhang C, Ung CY, Tripodis Y, Kanaan NM, Ikezu T, Cottone P, Leszyk J, Li H, Luebke J, Bryant CD, Wolozin B. Apicco DJ, et al. Among authors: ash pea. Nat Neurosci. 2018 Jan;21(1):72-80. doi: 10.1038/s41593-017-0022-z. Epub 2017 Nov 20. Nat Neurosci. 2018. PMID: 29273772 Free PMC article.
Pathological stress granules in Alzheimer's disease.
Ash PE, Vanderweyde TE, Youmans KL, Apicco DJ, Wolozin B. Ash PE, et al. Brain Res. 2014 Oct 10;1584:52-8. doi: 10.1016/j.brainres.2014.05.052. Epub 2014 Aug 7. Brain Res. 2014. PMID: 25108040 Free PMC article.
Interaction of tau with the RNA-Binding Protein TIA1 Regulates tau Pathophysiology and Toxicity.
Vanderweyde T, Apicco DJ, Youmans-Kidder K, Ash PEA, Cook C, Lummertz da Rocha E, Jansen-West K, Frame AA, Citro A, Leszyk JD, Ivanov P, Abisambra JF, Steffen M, Li H, Petrucelli L, Wolozin B. Vanderweyde T, et al. Among authors: ash pea. Cell Rep. 2016 May 17;15(7):1455-1466. doi: 10.1016/j.celrep.2016.04.045. Epub 2016 May 6. Cell Rep. 2016. PMID: 27160897 Free PMC article.
Dioxins and related environmental contaminants increase TDP-43 levels.
Ash PEA, Stanford EA, Al Abdulatif A, Ramirez-Cardenas A, Ballance HI, Boudeau S, Jeh A, Murithi JM, Tripodis Y, Murphy GJ, Sherr DH, Wolozin B. Ash PEA, et al. Mol Neurodegener. 2017 May 5;12(1):35. doi: 10.1186/s13024-017-0177-9. Mol Neurodegener. 2017. PMID: 28476168 Free PMC article.
Changes in neuronal immunofluorescence in the C- versus N-terminal domains of hnRNP H following D1 dopamine receptor activation.
Ruan QT, Yazdani N, Beierle JA, Hixson KM, Hokenson KE, Apicco DJ, Luttik KP, Zheng K, Maziuk BF, Ash PEA, Szumlinski KK, Russek SJ, Wolozin B, Bryant CD. Ruan QT, et al. Among authors: ash pea. Neurosci Lett. 2018 Sep 25;684:109-114. doi: 10.1016/j.neulet.2018.07.015. Epub 2018 Jul 9. Neurosci Lett. 2018. PMID: 30003938 Free PMC article.
RNA binding proteins co-localize with small tau inclusions in tauopathy.
Maziuk BF, Apicco DJ, Cruz AL, Jiang L, Ash PEA, da Rocha EL, Zhang C, Yu WH, Leszyk J, Abisambra JF, Li H, Wolozin B. Maziuk BF, et al. Among authors: ash pea. Acta Neuropathol Commun. 2018 Aug 1;6(1):71. doi: 10.1186/s40478-018-0574-5. Acta Neuropathol Commun. 2018. PMID: 30068389 Free PMC article.
Heavy Metal Neurotoxicants Induce ALS-Linked TDP-43 Pathology.
Ash PEA, Dhawan U, Boudeau S, Lei S, Carlomagno Y, Knobel M, Al Mohanna LFA, Boomhower SR, Newland MC, Sherr DH, Wolozin B. Ash PEA, et al. Toxicol Sci. 2019 Jan 1;167(1):105-115. doi: 10.1093/toxsci/kfy267. Toxicol Sci. 2019. PMID: 30371865 Free PMC article.
TIA1 regulates the generation and response to toxic tau oligomers.
Jiang L, Ash PEA, Maziuk BF, Ballance HI, Boudeau S, Abdullatif AA, Orlando M, Petrucelli L, Ikezu T, Wolozin B. Jiang L, et al. Among authors: ash pea. Acta Neuropathol. 2019 Feb;137(2):259-277. doi: 10.1007/s00401-018-1937-5. Epub 2018 Nov 21. Acta Neuropathol. 2019. PMID: 30465259 Free PMC article.
A Mutation in Hnrnph1 That Decreases Methamphetamine-Induced Reinforcement, Reward, and Dopamine Release and Increases Synaptosomal hnRNP H and Mitochondrial Proteins.
Ruan QT, Yazdani N, Blum BC, Beierle JA, Lin W, Coelho MA, Fultz EK, Healy AF, Shahin JR, Kandola AK, Luttik KP, Zheng K, Smith NJ, Cheung J, Mortazavi F, Apicco DJ, Ragu Varman D, Ramamoorthy S, Ash PEA, Rosene DL, Emili A, Wolozin B, Szumlinski KK, Bryant CD. Ruan QT, et al. Among authors: ash pea. J Neurosci. 2020 Jan 2;40(1):107-130. doi: 10.1523/JNEUROSCI.1808-19.2019. Epub 2019 Nov 8. J Neurosci. 2020. PMID: 31704785 Free PMC article.
30 results