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Molecular mechanisms of cereblon-based drugs.
Pharmacol Ther. 2019 Oct;202:132-139. doi: 10.1016/j.pharmthera.2019.06.004. Epub 2019 Jun 14.
Pharmacol Ther. 2019.
PMID: 31202702
Review.
Cereblon Control of Zebrafish Brain Size by Regulation of Neural Stem Cell Proliferation.
Ando H, Sato T, Ito T, Yamamoto J, Sakamoto S, Nitta N, Asatsuma-Okumura T, Shimizu N, Mizushima R, Aoki I, Imai T, Yamaguchi Y, Berk AJ, Handa H.
Ando H, et al. Among authors: asatsuma okumura t.
iScience. 2019 May 31;15:95-108. doi: 10.1016/j.isci.2019.04.007. Epub 2019 Apr 9.
iScience. 2019.
PMID: 31055217
Free PMC article.
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p63 is a cereblon substrate involved in thalidomide teratogenicity.
Asatsuma-Okumura T, Ando H, De Simone M, Yamamoto J, Sato T, Shimizu N, Asakawa K, Yamaguchi Y, Ito T, Guerrini L, Handa H.
Asatsuma-Okumura T, et al.
Nat Chem Biol. 2019 Nov;15(11):1077-1084. doi: 10.1038/s41589-019-0366-7. Epub 2019 Oct 7.
Nat Chem Biol. 2019.
PMID: 31591562
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Molecular Mechanisms of the Teratogenic Effects of Thalidomide.
Asatsuma-Okumura T, Ito T, Handa H.
Asatsuma-Okumura T, et al.
Pharmaceuticals (Basel). 2020 May 13;13(5):95. doi: 10.3390/ph13050095.
Pharmaceuticals (Basel). 2020.
PMID: 32414180
Free PMC article.
Review.
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PLZF and its fusion proteins are pomalidomide-dependent CRBN neosubstrates.
Shimizu N, Asatsuma-Okumura T, Yamamoto J, Yamaguchi Y, Handa H, Ito T.
Shimizu N, et al. Among authors: asatsuma okumura t.
Commun Biol. 2021 Nov 11;4(1):1277. doi: 10.1038/s42003-021-02801-y.
Commun Biol. 2021.
PMID: 34764413
Free PMC article.
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ARID2 is a pomalidomide-dependent CRL4CRBN substrate in multiple myeloma cells.
Yamamoto J, Suwa T, Murase Y, Tateno S, Mizutome H, Asatsuma-Okumura T, Shimizu N, Kishi T, Momose S, Kizaki M, Ito T, Yamaguchi Y, Handa H.
Yamamoto J, et al. Among authors: asatsuma okumura t.
Nat Chem Biol. 2020 Nov;16(11):1208-1217. doi: 10.1038/s41589-020-0645-3. Epub 2020 Sep 21.
Nat Chem Biol. 2020.
PMID: 32958952
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