Artsimovitch I - Search Results

1

Going Retro, Going Viral: Experiences and Lessons in Drug Discovery from COVID-19.

Wang B, Svetlov D, Bartikofsky D, Wobus CE, Artsimovitch I. Wang B, et al. Among authors: artsimovitch i. Molecules. 2022 Jun 14;27(12):3815. doi: 10.3390/molecules27123815. Molecules. 2022. PMID: 35744940 Free PMC article.

2

Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins.

Artsimovitch I, Vassylyeva MN, Svetlov D, Svetlov V, Perederina A, Igarashi N, Matsugaki N, Wakatsuki S, Tahirov TH, Vassylyev DG. Artsimovitch I, et al. Cell. 2005 Aug 12;122(3):351-63. doi: 10.1016/j.cell.2005.07.014. Cell. 2005. PMID: 16096056 Free article.

3

RNA polymerase gate loop guides the nontemplate DNA strand in transcription complexes.

NandyMazumdar M, Nedialkov Y, Svetlov D, Sevostyanova A, Belogurov GA, Artsimovitch I. NandyMazumdar M, et al. Among authors: artsimovitch i. Proc Natl Acad Sci U S A. 2016 Dec 27;113(52):14994-14999. doi: 10.1073/pnas.1613673114. Epub 2016 Dec 12. Proc Natl Acad Sci U S A. 2016. PMID: 27956639 Free PMC article.

4

Flipping states: a few key residues decide the winning conformation of the only universally conserved transcription factor.

Shi D, Svetlov D, Abagyan R, Artsimovitch I. Shi D, et al. Among authors: artsimovitch i. Nucleic Acids Res. 2017 Sep 6;45(15):8835-8843. doi: 10.1093/nar/gkx523. Nucleic Acids Res. 2017. PMID: 28605514 Free PMC article.

5

Locking the nontemplate DNA to control transcription.

Nedialkov Y, Svetlov D, Belogurov GA, Artsimovitch I. Nedialkov Y, et al. Among authors: artsimovitch i. Mol Microbiol. 2018 Aug;109(4):445-457. doi: 10.1111/mmi.13983. Mol Microbiol. 2018. PMID: 29758107 Free PMC article.

6

In silico discovery of small molecules that inhibit RfaH recruitment to RNA polymerase.

Svetlov D, Shi D, Twentyman J, Nedialkov Y, Rosen DA, Abagyan R, Artsimovitch I. Svetlov D, et al. Among authors: artsimovitch i. Mol Microbiol. 2018 Oct;110(1):128-142. doi: 10.1111/mmi.14093. Epub 2018 Oct 2. Mol Microbiol. 2018. PMID: 30069925 Free PMC article.

7

A Growing Gap between the RNAP and the Lead Ribosome.

Wang B, Artsimovitch I. Wang B, et al. Among authors: artsimovitch i. Trends Microbiol. 2021 Jan;29(1):4-5. doi: 10.1016/j.tim.2020.09.011. Epub 2020 Oct 10. Trends Microbiol. 2021. PMID: 33046341

8

Origins and Molecular Evolution of the NusG Paralog RfaH.

Wang B, Gumerov VM, Andrianova EP, Zhulin IB, Artsimovitch I. Wang B, et al. Among authors: artsimovitch i. mBio. 2020 Oct 27;11(5):e02717-20. doi: 10.1128/mBio.02717-20. mBio. 2020. PMID: 33109766 Free PMC article.

9

NusG, an Ancient Yet Rapidly Evolving Transcription Factor.

Wang B, Artsimovitch I. Wang B, et al. Among authors: artsimovitch i. Front Microbiol. 2021 Jan 8;11:619618. doi: 10.3389/fmicb.2020.619618. eCollection 2020. Front Microbiol. 2021. PMID: 33488562 Free PMC article. Review.

10

Allosteric Activation of SARS-CoV-2 RNA-Dependent RNA Polymerase by Remdesivir Triphosphate and Other Phosphorylated Nucleotides.

Wang B, Svetlov V, Wolf YI, Koonin EV, Nudler E, Artsimovitch I. Wang B, et al. Among authors: artsimovitch i. mBio. 2021 Jun 29;12(3):e0142321. doi: 10.1128/mBio.01423-21. Epub 2021 Jun 22. mBio. 2021. PMID: 34154407 Free PMC article.

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