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Blockade of TGF-β signaling reactivates HIV-1/SIV reservoirs and immune responses in vivo.
Samer S, Thomas Y, Araínga M, Carter C, Shirreff LM, Arif MS, Avita JM, Frank I, McRaven MD, Thuruthiyil CT, Heybeli VB, Anderson MR, Owen B, Gaisin A, Bose D, Simons LM, Hultquist JF, Arthos J, Cicala C, Sereti I, Santangelo PJ, Lorenzo-Redondo R, Hope TJ, Villinger FJ, Martinelli E. Samer S, et al. Among authors: arthos j. JCI Insight. 2022 Nov 8;7(21):e162290. doi: 10.1172/jci.insight.162290. JCI Insight. 2022. PMID: 36125890 Free PMC article.
HIV envelope induces a cascade of cell signals in non-proliferating target cells that favor virus replication.
Cicala C, Arthos J, Selig SM, Dennis G Jr, Hosack DA, Van Ryk D, Spangler ML, Steenbeke TD, Khazanie P, Gupta N, Yang J, Daucher M, Lempicki RA, Fauci AS. Cicala C, et al. Among authors: arthos j. Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9380-5. doi: 10.1073/pnas.142287999. Epub 2002 Jun 27. Proc Natl Acad Sci U S A. 2002. PMID: 12089333 Free PMC article.
HIV-1 gp120 induces NFAT nuclear translocation in resting CD4+ T-cells.
Cicala C, Arthos J, Censoplano N, Cruz C, Chung E, Martinelli E, Lempicki RA, Natarajan V, VanRyk D, Daucher M, Fauci AS. Cicala C, et al. Among authors: arthos j. Virology. 2006 Feb 5;345(1):105-14. doi: 10.1016/j.virol.2005.09.052. Epub 2005 Nov 2. Virology. 2006. PMID: 16260021 Free article.
R5 and X4 HIV envelopes induce distinct gene expression profiles in primary peripheral blood mononuclear cells.
Cicala C, Arthos J, Martinelli E, Censoplano N, Cruz CC, Chung E, Selig SM, Van Ryk D, Yang J, Jagannatha S, Chun TW, Ren P, Lempicki RA, Fauci AS. Cicala C, et al. Among authors: arthos j. Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3746-51. doi: 10.1073/pnas.0511237103. Epub 2006 Feb 27. Proc Natl Acad Sci U S A. 2006. PMID: 16505369 Free PMC article.
HIV-1 envelope protein binds to and signals through integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells.
Arthos J, Cicala C, Martinelli E, Macleod K, Van Ryk D, Wei D, Xiao Z, Veenstra TD, Conrad TP, Lempicki RA, McLaughlin S, Pascuccio M, Gopaul R, McNally J, Cruz CC, Censoplano N, Chung E, Reitano KN, Kottilil S, Goode DJ, Fauci AS. Arthos J, et al. Nat Immunol. 2008 Mar;9(3):301-9. doi: 10.1038/ni1566. Epub 2008 Feb 10. Nat Immunol. 2008. PMID: 18264102
135 results