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Improving CNS Delivery to Brain Metastases by Blood-Tumor Barrier Disruption.
Sprowls SA, Arsiwala TA, Bumgarner JR, Shah N, Lateef SS, Kielkowski BN, Lockman PR. Sprowls SA, et al. Among authors: arsiwala ta. Trends Cancer. 2019 Aug;5(8):495-505. doi: 10.1016/j.trecan.2019.06.003. Epub 2019 Jul 20. Trends Cancer. 2019. PMID: 31421906 Free PMC article. Review.
Hypomethylating Agent Azacitidine Is Effective in Treating Brain Metastasis Triple-Negative Breast Cancer Through Regulation of DNA Methylation of Keratin 18 Gene.
Butler C, Sprowls S, Szalai G, Arsiwala T, Saralkar P, Straight B, Hatcher S, Tyree E, Yost M, Kohler WJ, Wolff B, Putnam E, Lockman P, Liu T. Butler C, et al. Transl Oncol. 2020 Jun;13(6):100775. doi: 10.1016/j.tranon.2020.100775. Epub 2020 May 11. Transl Oncol. 2020. PMID: 32408199 Free PMC article.
Ultrasound-mediated disruption of the blood tumor barrier for improved therapeutic delivery.
Arsiwala TA, Sprowls SA, Blethen KE, Adkins CE, Saralkar PA, Fladeland RA, Pentz W, Gabriele A, Kielkowski B, Mehta RI, Wang P, Carpenter JS, Ranjan M, Najib U, Rezai AR, Lockman PR. Arsiwala TA, et al. Neoplasia. 2021 Jul;23(7):676-691. doi: 10.1016/j.neo.2021.04.005. Epub 2021 Jun 14. Neoplasia. 2021. PMID: 34139452 Free PMC article. Review.
Modulation of the blood-tumor barrier to enhance drug delivery and efficacy for brain metastases.
Blethen KE, Arsiwala TA, Fladeland RA, Sprowls SA, Panchal DM, Adkins CE, Kielkowski BN, Earp LE, Glass MJ, Pritt TA, Cabuyao YM, Aulakh S, Lockman PR. Blethen KE, et al. Among authors: arsiwala ta. Neurooncol Adv. 2021 Nov 27;3(Suppl 5):v133-v143. doi: 10.1093/noajnl/vdab123. eCollection 2021 Nov. Neurooncol Adv. 2021. PMID: 34859240 Free PMC article.
Characterization of passive permeability after low intensity focused ultrasound mediated blood-brain barrier disruption in a preclinical model.
Arsiwala TA, Sprowls SA, Blethen KE, Fladeland RA, Wolford CP, Kielkowski BN, Glass MJ, Wang P, Wilson O, Carpenter JS, Ranjan M, Finomore V, Rezai A, Lockman PR. Arsiwala TA, et al. Fluids Barriers CNS. 2022 Sep 8;19(1):72. doi: 10.1186/s12987-022-00369-1. Fluids Barriers CNS. 2022. PMID: 36076213 Free PMC article.
Blood-tumor barrier opening by MRI-guided transcranial focused ultrasound in a preclinical breast cancer brain metastasis model improves efficacy of combinatorial chemotherapy.
Arsiwala TA, Blethen KE, Wolford CP, Panchal DM, Sprowls SA, Fladeland RA, Kielkowski BN, Pritt TA, Wang P, Wilson O, Carpenter JS, Finomore V, Rezai A, Lockman PR. Arsiwala TA, et al. Front Oncol. 2023 Feb 10;13:1104594. doi: 10.3389/fonc.2023.1104594. eCollection 2023. Front Oncol. 2023. PMID: 36845739 Free PMC article.
15 results