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Longitudinal analyses of CLL in mice identify leukemia-related clonal changes including a Myc gain predicting poor outcome in patients.
Öztürk S, Paul Y, Afzal S, Gil-Farina I, Jauch A, Bruch PM, Kalter V, Hanna B, Arseni L, Roessner PM, Schmidt M, Stilgenbauer S, Dietrich S, Lichter P, Zapatka M, Seiffert M. Öztürk S, et al. Among authors: arseni l. Leukemia. 2022 Feb;36(2):464-475. doi: 10.1038/s41375-021-01381-4. Epub 2021 Aug 20. Leukemia. 2022. PMID: 34417556 Free PMC article.
EOMES and IL-10 regulate antitumor activity of T regulatory type 1 CD4+ T cells in chronic lymphocytic leukemia.
Roessner PM, Llaó Cid L, Lupar E, Roider T, Bordas M, Schifflers C, Arseni L, Gaupel AC, Kilpert F, Krötschel M, Arnold SJ, Sellner L, Colomer D, Stilgenbauer S, Dietrich S, Lichter P, Izcue A, Seiffert M. Roessner PM, et al. Among authors: arseni l. Leukemia. 2021 Aug;35(8):2311-2324. doi: 10.1038/s41375-021-01136-1. Epub 2021 Feb 1. Leukemia. 2021. PMID: 33526861 Free PMC article.
T-bet suppresses proliferation of malignant B cells in chronic lymphocytic leukemia.
Roessner PM, Seufert I, Chapaprieta V, Jayabalan R, Briesch H, Massoni-Badosa R, Boskovic P, Beckendorff J, Roider T, Arseni L, Coelho M, Chakraborty S, Vaca A, Sivina M, Muckenhuber M, Rodriguez-Rodriguez S, Bonato A, Herbst SA, Zapatka M, Sun C, Kretzmer H, Naake T, Bruch PM, Czernilofsky F, Ten Hacken E, Schneider M, Helm D, Yosifov DY, Kauer J, Danilov AV, Bewarder M, Heyne K, Schneider C, Stilgenbauer S, Wiestner A, Mallm JP, Burger JA, Efremov DG, Lichter P, Dietrich S, Martín-Subero JI, Rippe K, Seiffert M. Roessner PM, et al. Among authors: arseni l. Blood. 2024 Apr 29:blood.2023021990. doi: 10.1182/blood.2023021990. Online ahead of print. Blood. 2024. PMID: 38684038