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105 results

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Page 1
TGFβ2 and TGFβ3 isoforms drive fibrotic disease pathogenesis.
Sun T, Huang Z, Liang WC, Yin J, Lin WY, Wu J, Vernes JM, Lutman J, Caplazi P, Jeet S, Wong T, Wong M, DePianto DJ, Morshead KB, Sun KH, Modrusan Z, Vander Heiden JA, Abbas AR, Zhang H, Xu M, N'Diaye EN, Roose-Girma M, Wolters PJ, Yadav R, Sukumaran S, Ghilardi N, Corpuz R, Emson C, Meng YG, Ramalingam TR, Lupardus P, Brightbill HD, Seshasayee D, Wu Y, Arron JR. Sun T, et al. Among authors: arron jr. Sci Transl Med. 2021 Aug 4;13(605):eabe0407. doi: 10.1126/scitranslmed.abe0407. Sci Transl Med. 2021. PMID: 34349032
Blood transcriptomic signature in type-2 biomarker-low severe asthma and asthma control.
Zeng X, Qing J, Li CM, Lu J, Yamawaki T, Hsu YH, Vander Lugt B, Hsu H, Busby J, McDowell PJ, Jackson DJ, Djukanovic R, Matthews JG, Arron JR, Bradding P, Brightling CE, Chaudhuri R, Choy DF, Cowan D, Fowler SJ, Hardman TC, Harrison T, Howarth P, Lordan J, Mansur AH, Menzies-Gow A, Pavord ID, Walker S, Woodcock A, Heaney LG; investigators for the UK MRC Refractory Asthma Stratification Program (RASP-UK). Zeng X, et al. Among authors: arron jr. J Allergy Clin Immunol. 2023 Oct;152(4):876-886. doi: 10.1016/j.jaci.2023.05.023. Epub 2023 Jun 12. J Allergy Clin Immunol. 2023. PMID: 37315813 Free article. Clinical Trial.
T-helper type 2-driven inflammation defines major subphenotypes of asthma.
Woodruff PG, Modrek B, Choy DF, Jia G, Abbas AR, Ellwanger A, Koth LL, Arron JR, Fahy JV. Woodruff PG, et al. Among authors: arron jr. Am J Respir Crit Care Med. 2009 Sep 1;180(5):388-95. doi: 10.1164/rccm.200903-0392OC. Epub 2009 May 29. Am J Respir Crit Care Med. 2009. PMID: 19483109 Free PMC article. Clinical Trial.
Lung gene expression in a rhesus allergic asthma model correlates with physiologic parameters of disease and exhibits common and distinct pathways with human asthma and a mouse asthma model.
Abbas AR, Jackman JK, Bullens SL, Davis SM, Choy DF, Fedorowicz G, Tan M, Truong BT, Gloria Meng Y, Diehl L, Miller LA, Schelegle ES, Hyde DM, Clark HF, Modrusan Z, Arron JR, Wu LC. Abbas AR, et al. Among authors: arron jr. Am J Pathol. 2011 Oct;179(4):1667-80. doi: 10.1016/j.ajpath.2011.06.009. Epub 2011 Aug 3. Am J Pathol. 2011. PMID: 21819959 Free PMC article.
Endogenously expressed IL-13Rα2 attenuates IL-13-mediated responses but does not activate signaling in human lung fibroblasts.
Chandriani S, DePianto DJ, N'Diaye EN, Abbas AR, Jackman J, Bevers J 3rd, Ramirez-Carrozzi V, Pappu R, Kauder SE, Toy K, Ha C, Modrusan Z, Wu LC, Collard HR, Wolters PJ, Egen JG, Arron JR. Chandriani S, et al. Among authors: arron jr. J Immunol. 2014 Jul 1;193(1):111-9. doi: 10.4049/jimmunol.1301761. Epub 2014 May 30. J Immunol. 2014. PMID: 24879793 Clinical Trial.
Heterogeneous gene expression signatures correspond to distinct lung pathologies and biomarkers of disease severity in idiopathic pulmonary fibrosis.
DePianto DJ, Chandriani S, Abbas AR, Jia G, N'Diaye EN, Caplazi P, Kauder SE, Biswas S, Karnik SK, Ha C, Modrusan Z, Matthay MA, Kukreja J, Collard HR, Egen JG, Wolters PJ, Arron JR. DePianto DJ, et al. Among authors: arron jr. Thorax. 2015 Jan;70(1):48-56. doi: 10.1136/thoraxjnl-2013-204596. Epub 2014 Sep 12. Thorax. 2015. PMID: 25217476 Free PMC article.
A microRNA upregulated in asthma airway T cells promotes TH2 cytokine production.
Simpson LJ, Patel S, Bhakta NR, Choy DF, Brightbill HD, Ren X, Wang Y, Pua HH, Baumjohann D, Montoya MM, Panduro M, Remedios KA, Huang X, Fahy JV, Arron JR, Woodruff PG, Ansel KM. Simpson LJ, et al. Among authors: arron jr. Nat Immunol. 2014 Dec;15(12):1162-70. doi: 10.1038/ni.3026. Epub 2014 Nov 2. Nat Immunol. 2014. PMID: 25362490 Free PMC article.
105 results