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Calcium modulates the domain flexibility and function of an α-actinin similar to the ancestral α-actinin.
Pinotsis N, Zielinska K, Babuta M, Arolas JL, Kostan J, Khan MB, Schreiner C, Salmazo A, Ciccarelli L, Puchinger M, Gkougkoulia EA, Ribeiro EA Jr, Marlovits TC, Bhattacharya A, Djinovic-Carugo K. Pinotsis N, et al. Among authors: arolas jl. Proc Natl Acad Sci U S A. 2020 Sep 8;117(36):22101-22112. doi: 10.1073/pnas.1917269117. Epub 2020 Aug 26. Proc Natl Acad Sci U S A. 2020. PMID: 32848067 Free PMC article.
Order from disorder in the sarcomere: FATZ forms a fuzzy but tight complex and phase-separated condensates with α-actinin.
Sponga A, Arolas JL, Schwarz TC, Jeffries CM, Rodriguez Chamorro A, Kostan J, Ghisleni A, Drepper F, Polyansky A, De Almeida Ribeiro E, Pedron M, Zawadzka-Kazimierczuk A, Mlynek G, Peterbauer T, Doto P, Schreiner C, Hollerl E, Mateos B, Geist L, Faulkner G, Kozminski W, Svergun DI, Warscheid B, Zagrovic B, Gautel M, Konrat R, Djinović-Carugo K. Sponga A, et al. Among authors: arolas jl. Sci Adv. 2021 May 28;7(22):eabg7653. doi: 10.1126/sciadv.abg7653. Print 2021 May. Sci Adv. 2021. PMID: 34049882 Free PMC article.
Ultratight crystal packing of a 10 kDa protein.
Trillo-Muyo S, Jasilionis A, Domagalski MJ, Chruszcz M, Minor W, Kuisiene N, Arolas JL, Solà M, Gomis-Rüth FX. Trillo-Muyo S, et al. Among authors: arolas jl. Acta Crystallogr D Biol Crystallogr. 2013 Mar;69(Pt 3):464-70. doi: 10.1107/S0907444912050135. Epub 2013 Feb 16. Acta Crystallogr D Biol Crystallogr. 2013. PMID: 23519421 Free PMC article.
38 results