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Exposure to environmental contaminants is associated with altered hepatic lipid metabolism in non-alcoholic fatty liver disease.
Sen P, Qadri S, Luukkonen PK, Ragnarsdottir O, McGlinchey A, Jäntti S, Juuti A, Arola J, Schlezinger JJ, Webster TF, Orešič M, Yki-Järvinen H, Hyötyläinen T. Sen P, et al. Among authors: arola j. J Hepatol. 2022 Feb;76(2):283-293. doi: 10.1016/j.jhep.2021.09.039. Epub 2021 Oct 7. J Hepatol. 2022. PMID: 34627976 Free article.
A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans.
Kotronen A, Johansson LE, Johansson LM, Roos C, Westerbacka J, Hamsten A, Bergholm R, Arkkila P, Arola J, Kiviluoto T, Fisher RM, Ehrenborg E, Orho-Melander M, Ridderstråle M, Groop L, Yki-Järvinen H. Kotronen A, et al. Among authors: arola j. Diabetologia. 2009 Jun;52(6):1056-60. doi: 10.1007/s00125-009-1285-z. Epub 2009 Feb 18. Diabetologia. 2009. PMID: 19224197 Free article.
Splanchnic balance of free fatty acids, endocannabinoids, and lipids in subjects with nonalcoholic fatty liver disease.
Westerbacka J, Kotronen A, Fielding BA, Wahren J, Hodson L, Perttilä J, Seppänen-Laakso T, Suortti T, Arola J, Hultcrantz R, Castillo S, Olkkonen VM, Frayn KN, Orešič M, Yki-Järvinen H. Westerbacka J, et al. Among authors: arola j. Gastroenterology. 2010 Dec;139(6):1961-1971.e1. doi: 10.1053/j.gastro.2010.06.064. Epub 2010 Jun 27. Gastroenterology. 2010. PMID: 20600015 Clinical Trial.
Prediction of non-alcoholic fatty-liver disease and liver fat content by serum molecular lipids.
Orešič M, Hyötyläinen T, Kotronen A, Gopalacharyulu P, Nygren H, Arola J, Castillo S, Mattila I, Hakkarainen A, Borra RJ, Honka MJ, Verrijken A, Francque S, Iozzo P, Leivonen M, Jaser N, Juuti A, Sørensen TI, Nuutila P, Van Gaal L, Yki-Järvinen H. Orešič M, et al. Among authors: arola j. Diabetologia. 2013 Oct;56(10):2266-74. doi: 10.1007/s00125-013-2981-2. Epub 2013 Jul 4. Diabetologia. 2013. PMID: 23824212 Free PMC article.
A population-based study on the prevalence of NASH using scores validated against liver histology.
Hyysalo J, Männistö VT, Zhou Y, Arola J, Kärjä V, Leivonen M, Juuti A, Jaser N, Lallukka S, Käkelä P, Venesmaa S, Simonen M, Saltevo J, Moilanen L, Korpi-Hyövalti E, Keinänen-Kiukaanniemi S, Oksa H, Orho-Melander M, Valenti L, Fargion S, Pihlajamäki J, Peltonen M, Yki-Järvinen H. Hyysalo J, et al. Among authors: arola j. J Hepatol. 2014 Apr;60(4):839-46. doi: 10.1016/j.jhep.2013.12.009. Epub 2013 Dec 12. J Hepatol. 2014. PMID: 24333862
Ketone body production is differentially altered in steatosis and non-alcoholic steatohepatitis in obese humans.
Männistö VT, Simonen M, Hyysalo J, Soininen P, Kangas AJ, Kaminska D, Matte AK, Venesmaa S, Käkelä P, Kärjä V, Arola J, Gylling H, Cederberg H, Kuusisto J, Laakso M, Yki-Järvinen H, Ala-Korpela M, Pihlajamäki J. Männistö VT, et al. Among authors: arola j. Liver Int. 2015 Jul;35(7):1853-61. doi: 10.1111/liv.12769. Epub 2015 Jan 20. Liver Int. 2015. PMID: 25533197
201 results