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SETD2 non genomic loss of function in advanced systemic mastocytosis is mediated by an Aurora kinase A/MDM2 axis and can be therapeutically targeted.
Mancini M, Monaldi C, De Santis S, Papayannidis C, Rondoni M, Sartor C, Bruno S, Pagano L, Criscuolo M, Zanotti R, Bonifacio M, Tosi P, Arock M, Valent P, Cavo M, Soverini S. Mancini M, et al. Among authors: arock m. Biomark Res. 2023 Mar 10;11(1):29. doi: 10.1186/s40364-023-00468-7. Biomark Res. 2023. PMID: 36894973 Free PMC article.
Diagnosis and treatment of systemic mastocytosis: state of the art.
Valent P, Akin C, Sperr WR, Horny HP, Arock M, Lechner K, Bennett JM, Metcalfe DD. Valent P, et al. Among authors: arock m. Br J Haematol. 2003 Sep;122(5):695-717. doi: 10.1046/j.1365-2141.2003.04575.x. Br J Haematol. 2003. PMID: 12930381 Free article. Review. No abstract available.
On the way to targeted therapy of mast cell neoplasms: identification of molecular targets in neoplastic mast cells and evaluation of arising treatment concepts.
Valent P, Ghannadan M, Akin C, Krauth MT, Selzer E, Mayerhofer M, Sperr WR, Arock M, Samorapoompichit P, Horny HP, Metcalfe DD. Valent P, et al. Among authors: arock m. Eur J Clin Invest. 2004 Aug;34 Suppl 2:41-52. doi: 10.1111/j.0960-135X.2004.01369.x. Eur J Clin Invest. 2004. PMID: 15291805 Review.
Mastocytosis: pathology, genetics, and current options for therapy.
Valent P, Akin C, Sperr WR, Mayerhofer M, Födinger M, Fritsche-Polanz R, Sotlar K, Escribano L, Arock M, Horny HP, Metcalfe DD. Valent P, et al. Among authors: arock m. Leuk Lymphoma. 2005 Jan;46(1):35-48. doi: 10.1080/10428190400010775. Leuk Lymphoma. 2005. PMID: 15621779 Review.
The serum tryptase test: an emerging robust biomarker in clinical hematology.
Valent P, Sperr WR, Sotlar K, Reiter A, Akin C, Gotlib J, Horny HP, Arock M. Valent P, et al. Among authors: arock m. Expert Rev Hematol. 2014 Oct;7(5):683-90. doi: 10.1586/17474086.2014.955008. Epub 2014 Aug 28. Expert Rev Hematol. 2014. PMID: 25169217 Free PMC article. Review.
257 results