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Vasoinhibins prevent retinal vasopermeability associated with diabetic retinopathy in rats via protein phosphatase 2A-dependent eNOS inactivation.
García C, Aranda J, Arnold E, Thébault S, Macotela Y, López-Casillas F, Mendoza V, Quiroz-Mercado H, Hernández-Montiel HL, Lin SH, de la Escalera GM, Clapp C. García C, et al. Among authors: arnold e. J Clin Invest. 2008 Jun;118(6):2291-300. doi: 10.1172/JCI34508. J Clin Invest. 2008. PMID: 18497878 Free PMC article.
Vasoinhibins: novel inhibitors of ocular angiogenesis.
Clapp C, Thebault S, Arnold E, García C, Rivera JC, de la Escalera GM. Clapp C, et al. Among authors: arnold e. Am J Physiol Endocrinol Metab. 2008 Oct;295(4):E772-8. doi: 10.1152/ajpendo.90358.2008. Epub 2008 Jun 10. Am J Physiol Endocrinol Metab. 2008. PMID: 18544641 Free article. Review.
Diabetes enhances the efficacy of AAV2 vectors in the retina: therapeutic effect of AAV2 encoding vasoinhibin and soluble VEGF receptor 1.
Díaz-Lezama N, Wu Z, Adán-Castro E, Arnold E, Vázquez-Membrillo M, Arredondo-Zamarripa D, Ledesma-Colunga MG, Moreno-Carranza B, Martinez de la Escalera G, Colosi P, Clapp C. Díaz-Lezama N, et al. Among authors: arnold e. Lab Invest. 2016 Mar;96(3):283-95. doi: 10.1038/labinvest.2015.135. Epub 2015 Nov 16. Lab Invest. 2016. PMID: 26568297 Free article.
Prolactin protects retinal pigment epithelium by inhibiting sirtuin 2-dependent cell death.
Meléndez García R, Arredondo Zamarripa D, Arnold E, Ruiz-Herrera X, Noguez Imm R, Baeza Cruz G, Adán N, Binart N, Riesgo-Escovar J, Goffin V, Ordaz B, Peña-Ortega F, Martínez-Torres A, Clapp C, Thebault S. Meléndez García R, et al. Among authors: arnold e. EBioMedicine. 2016 May;7:35-49. doi: 10.1016/j.ebiom.2016.03.048. Epub 2016 Apr 20. EBioMedicine. 2016. PMID: 27322457 Free PMC article.
Cathepsin D is the primary protease for the generation of adenohypophyseal vasoinhibins: cleavage occurs within the prolactin secretory granules.
Cruz-Soto ME, Cosío G, Jeziorski MC, Vargas-Barroso V, Aguilar MB, Cárabez A, Berger P, Saftig P, Arnold E, Thebault S, Martínez de la Escalera G, Clapp C. Cruz-Soto ME, et al. Among authors: arnold e. Endocrinology. 2009 Dec;150(12):5446-54. doi: 10.1210/en.2009-0390. Epub 2009 Oct 9. Endocrinology. 2009. PMID: 19819948
917 results