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Page 1
Metastatic Prostate Cancers with BRCA2 versus ATM Mutations Exhibit Divergent Molecular Features and Clinical Outcomes.
Hwang J, Shi X, Elliott A, Arnoff TE, McGrath J, Xiu J, Walker P, Bergom HE, Day A, Ahmed S, Tape S, Makovec A, Ali A, Shaker RM, Toye E, Passow R, Lozada JR, Wang J, Lou E, Mouw KW, Carneiro BA, Heath EI, McKay RR, Korn WM, Nabhan C, Ryan CJ, Antonarakis ES. Hwang J, et al. Among authors: arnoff te. Clin Cancer Res. 2023 Jul 14;29(14):2702-2713. doi: 10.1158/1078-0432.CCR-22-3394. Clin Cancer Res. 2023. PMID: 37126020
CREB5 reprograms FOXA1 nuclear interactions to promote resistance to androgen receptor-targeting therapies.
Hwang JH, Arafeh R, Seo JH, Baca SC, Ludwig M, Arnoff TE, Sawyer L, Richter C, Tape S, Bergom HE, McSweeney S, Rennhack JP, Klingenberg SA, Cheung ATM, Kwon J, So J, Kregel S, Van Allen EM, Drake JM, Freedman ML, Hahn WC. Hwang JH, et al. Among authors: arnoff te. Elife. 2022 May 12;11:e73223. doi: 10.7554/eLife.73223. Elife. 2022. PMID: 35550030 Free PMC article.
MDM2 and MDM4 Are Therapeutic Vulnerabilities in Malignant Rhabdoid Tumors.
Howard TP, Arnoff TE, Song MR, Giacomelli AO, Wang X, Hong AL, Dharia NV, Wang S, Vazquez F, Pham MT, Morgan AM, Wachter F, Bird GH, Kugener G, Oberlick EM, Rees MG, Tiv HL, Hwang JH, Walsh KH, Cook A, Krill-Burger JM, Tsherniak A, Gokhale PC, Park PJ, Stegmaier K, Walensky LD, Hahn WC, Roberts CWM. Howard TP, et al. Among authors: arnoff te. Cancer Res. 2019 May 1;79(9):2404-2414. doi: 10.1158/0008-5472.CAN-18-3066. Epub 2019 Feb 12. Cancer Res. 2019. PMID: 30755442 Free PMC article.
Rhabdoid Tumors Are Sensitive to the Protein-Translation Inhibitor Homoharringtonine.
Howard TP, Oberlick EM, Rees MG, Arnoff TE, Pham MT, Brenan L, DoCarmo M, Hong AL, Kugener G, Chou HC, Drosos Y, Mathias KM, Ramos P, Seashore-Ludlow B, Giacomelli AO, Wang X, Freeman BB 3rd, Blankenship K, Hoffmann L, Tiv HL, Gokhale PC, Johannessen CM, Stewart EA, Schreiber SL, Hahn WC, Roberts CWM. Howard TP, et al. Among authors: arnoff te. Clin Cancer Res. 2020 Sep 15;26(18):4995-5006. doi: 10.1158/1078-0432.CCR-19-2717. Epub 2020 Jul 6. Clin Cancer Res. 2020. PMID: 32631955 Free PMC article.
SMAD4 represses FOSL1 expression and pancreatic cancer metastatic colonization.
Dai C, Rennhack JP, Arnoff TE, Thaker M, Younger ST, Doench JG, Huang AY, Yang A, Aguirre AJ, Wang B, Mun E, O'Connell JT, Huang Y, Labella K, Talamas JA, Li J, Ilic N, Hwang J, Hong AL, Giacomelli AO, Gjoerup O, Root DE, Hahn WC. Dai C, et al. Among authors: arnoff te. Cell Rep. 2021 Jul 27;36(4):109443. doi: 10.1016/j.celrep.2021.109443. Cell Rep. 2021. PMID: 34320363 Free PMC article.
Biologically informed deep neural network for prostate cancer discovery.
Elmarakeby HA, Hwang J, Arafeh R, Crowdis J, Gang S, Liu D, AlDubayan SH, Salari K, Kregel S, Richter C, Arnoff TE, Park J, Hahn WC, Van Allen EM. Elmarakeby HA, et al. Among authors: arnoff te. Nature. 2021 Oct;598(7880):348-352. doi: 10.1038/s41586-021-03922-4. Epub 2021 Sep 22. Nature. 2021. PMID: 34552244 Free PMC article.
The role of p53 in anti-tumor immunity and response to immunotherapy.
Carlsen L, Zhang S, Tian X, De La Cruz A, George A, Arnoff TE, El-Deiry WS. Carlsen L, et al. Among authors: arnoff te. Front Mol Biosci. 2023 Aug 1;10:1148389. doi: 10.3389/fmolb.2023.1148389. eCollection 2023. Front Mol Biosci. 2023. PMID: 37602328 Free PMC article. Review.
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