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VHL loss reprograms the immune landscape to promote an inflammatory myeloid microenvironment in renal tumorigenesis.
Wolf MM, Madden MZ, Arner EN, Bader JE, Ye X, Vlach L, Tigue ML, Landis MD, Jonker PB, Hatem Z, Steiner KK, Gaines DK, Reinfeld BI, Hathaway ES, Xin F, Tantawy MN, Haake SM, Jonasch E, Muir A, Weiss VL, Beckermann KE, Rathmell WK, Rathmell JC. Wolf MM, et al. Among authors: arner en. J Clin Invest. 2024 Apr 15;134(8):e173934. doi: 10.1172/JCI173934. J Clin Invest. 2024. PMID: 38618956 Free PMC article.
Deep Learning-Based H-Score Quantification of Immunohistochemistry-Stained Images.
Wen Z, Luo D, Wang S, Rong R, Evers BM, Jia L, Fang Y, Daoud EV, Yang S, Gu Z, Arner EN, Lewis CM, Solis Soto LM, Fujimoto J, Behrens C, Wistuba II, Yang DM, Brekken RA, O'Donnell KA, Xie Y, Xiao G. Wen Z, et al. Among authors: arner en. Mod Pathol. 2024 Feb;37(2):100398. doi: 10.1016/j.modpat.2023.100398. Epub 2023 Dec 1. Mod Pathol. 2024. PMID: 38043788
Clozapine suppresses NADPH oxidase activation, counteracts cytosolic H2O2, and triggers early onset mitochondrial dysfunction during adipogenesis of human liposarcoma SW872 cells.
Blandino G, Fiorani M, Canonico B, De Matteis R, Guidarelli A, Montanari M, Buffi G, Coppo L, Arnér ESJ, Cantoni O. Blandino G, et al. Among authors: arner esj. Redox Biol. 2023 Nov;67:102915. doi: 10.1016/j.redox.2023.102915. Epub 2023 Oct 12. Redox Biol. 2023. PMID: 37866162 Free PMC article.
Gut microbial carbohydrate metabolism contributes to insulin resistance.
Takeuchi T, Kubota T, Nakanishi Y, Tsugawa H, Suda W, Kwon AT, Yazaki J, Ikeda K, Nemoto S, Mochizuki Y, Kitami T, Yugi K, Mizuno Y, Yamamichi N, Yamazaki T, Takamoto I, Kubota N, Kadowaki T, Arner E, Carninci P, Ohara O, Arita M, Hattori M, Koyasu S, Ohno H. Takeuchi T, et al. Among authors: arner e. Nature. 2023 Sep;621(7978):389-395. doi: 10.1038/s41586-023-06466-x. Epub 2023 Aug 30. Nature. 2023. PMID: 37648852 Free PMC article.
351 results