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Ref-1 redox activity alters cancer cell metabolism in pancreatic cancer: exploiting this novel finding as a potential target.
Gampala S, Shah F, Lu X, Moon HR, Babb O, Umesh Ganesh N, Sandusky G, Hulsey E, Armstrong L, Mosely AL, Han B, Ivan M, Yeh JJ, Kelley MR, Zhang C, Fishel ML. Gampala S, et al. Among authors: armstrong l. J Exp Clin Cancer Res. 2021 Aug 10;40(1):251. doi: 10.1186/s13046-021-02046-x. J Exp Clin Cancer Res. 2021. PMID: 34376225 Free PMC article.
Combined inhibition of Ref-1 and STAT3 leads to synergistic tumour inhibition in multiple cancers using 3D and in vivo tumour co-culture models.
Caston RA, Shah F, Starcher CL, Wireman R, Babb O, Grimard M, McGeown J, Armstrong L, Tong Y, Pili R, Rupert J, Zimmers TA, Elmi AN, Pollok KE, Motea EA, Kelley MR, Fishel ML. Caston RA, et al. Among authors: armstrong l. J Cell Mol Med. 2021 Jan;25(2):784-800. doi: 10.1111/jcmm.16132. Epub 2020 Dec 3. J Cell Mol Med. 2021. PMID: 33274592 Free PMC article.
RelA Is an Essential Target for Enhancing Cellular Responses to the DNA Repair/Ref-1 Redox Signaling Protein and Restoring Perturbated Cellular Redox Homeostasis in Mouse PDAC Cells.
Mijit M, Wireman R, Armstrong L, Gampala S, Hassan Z, Schneeweis C, Schneider G, Zhang C, Fishel ML, Kelley MR. Mijit M, et al. Among authors: armstrong l. Front Oncol. 2022 Mar 24;12:826617. doi: 10.3389/fonc.2022.826617. eCollection 2022. Front Oncol. 2022. PMID: 35402225 Free PMC article.
SCH 51344 inhibits ras transformation by a novel mechanism.
Kumar CC, Prorock-Rogers C, Kelly J, Dong Z, Lin JJ, Armstrong L, Kung HF, Weber MJ, Afonso A. Kumar CC, et al. Among authors: armstrong l. Cancer Res. 1995 Nov 1;55(21):5106-17. Cancer Res. 1995. PMID: 7585559
Integrin alpha(v)beta(3)-mediated activation of apoptosis.
Brassard DL, Maxwell E, Malkowski M, Nagabhushan TL, Kumar CC, Armstrong L. Brassard DL, et al. Among authors: armstrong l. Exp Cell Res. 1999 Aug 25;251(1):33-45. doi: 10.1006/excr.1999.4559. Exp Cell Res. 1999. PMID: 10438569
959 results