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Highly diastereoselective heterogeneously catalyzed hydrogenation of enamines for the synthesis of chiral beta-amino acid derivatives.
Ikemoto N, Tellers DM, Dreher SD, Liu J, Huang A, Rivera NR, Njolito E, Hsiao Y, McWilliams JC, Williams JM, Armstrong JD 3rd, Sun Y, Mathre DJ, Grabowski EJ, Tillyer RD. Ikemoto N, et al. Among authors: armstrong jd 3rd. J Am Chem Soc. 2004 Mar 17;126(10):3048-9. doi: 10.1021/ja038812t. J Am Chem Soc. 2004. PMID: 15012124
Highly efficient asymmetric synthesis of sitagliptin.
Hansen KB, Hsiao Y, Xu F, Rivera N, Clausen A, Kubryk M, Krska S, Rosner T, Simmons B, Balsells J, Ikemoto N, Sun Y, Spindler F, Malan C, Grabowski EJ, Armstrong JD 3rd. Hansen KB, et al. Among authors: armstrong jd 3rd. J Am Chem Soc. 2009 Jul 1;131(25):8798-804. doi: 10.1021/ja902462q. J Am Chem Soc. 2009. PMID: 19507853
Practical preparation of 3,3-difluoropyrrolidine.
Xu F, Simmons B, Armstrong J 3rd, Murry J. Xu F, et al. Among authors: armstrong j 3rd. J Org Chem. 2005 Jul 22;70(15):6105-7. doi: 10.1021/jo050591h. J Org Chem. 2005. PMID: 16018711
2,567 results