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A catalytically silent FAAH-1 variant drives anandamide transport in neurons.
Fu J, Bottegoni G, Sasso O, Bertorelli R, Rocchia W, Masetti M, Guijarro A, Lodola A, Armirotti A, Garau G, Bandiera T, Reggiani A, Mor M, Cavalli A, Piomelli D. Fu J, et al. Among authors: armirotti a. Nat Neurosci. 2011 Nov 20;15(1):64-9. doi: 10.1038/nn.2986. Nat Neurosci. 2011. PMID: 22101642 Free PMC article.
Synthesis and structure-activity relationship (SAR) of 2-methyl-4-oxo-3-oxetanylcarbamic acid esters, a class of potent N-acylethanolamine acid amidase (NAAA) inhibitors.
Ponzano S, Bertozzi F, Mengatto L, Dionisi M, Armirotti A, Romeo E, Berteotti A, Fiorelli C, Tarozzo G, Reggiani A, Duranti A, Tarzia G, Mor M, Cavalli A, Piomelli D, Bandiera T. Ponzano S, et al. Among authors: armirotti a. J Med Chem. 2013 Sep 12;56(17):6917-34. doi: 10.1021/jm400739u. Epub 2013 Aug 30. J Med Chem. 2013. PMID: 23991897 Free article.
Synthesis, structure-activity, and structure-stability relationships of 2-substituted-N-(4-oxo-3-oxetanyl) N-acylethanolamine acid amidase (NAAA) inhibitors.
Vitale R, Ottonello G, Petracca R, Bertozzi SM, Ponzano S, Armirotti A, Berteotti A, Dionisi M, Cavalli A, Piomelli D, Bandiera T, Bertozzi F. Vitale R, et al. Among authors: armirotti a. ChemMedChem. 2014 Feb;9(2):323-36. doi: 10.1002/cmdc.201300416. Epub 2014 Jan 8. ChemMedChem. 2014. PMID: 24403170 Free article.
Role of oleoylethanolamide as a feeding regulator in goldfish.
Tinoco AB, Armirotti A, Isorna E, Delgado MJ, Piomelli D, de Pedro N. Tinoco AB, et al. Among authors: armirotti a. J Exp Biol. 2014 Aug 1;217(Pt 15):2761-9. doi: 10.1242/jeb.106161. Epub 2014 May 22. J Exp Biol. 2014. PMID: 24855680
Structural determinants of peripheral O-arylcarbamate FAAH inhibitors render them dual substrates for Abcb1 and Abcg2 and restrict their access to the brain.
Moreno-Sanz G, Barrera B, Armirotti A, Bertozzi SM, Scarpelli R, Bandiera T, Prieto JG, Duranti A, Tarzia G, Merino G, Piomelli D. Moreno-Sanz G, et al. Among authors: armirotti a. Pharmacol Res. 2014 Sep;87:87-93. doi: 10.1016/j.phrs.2014.06.004. Epub 2014 Jun 30. Pharmacol Res. 2014. PMID: 24993496 Free PMC article.
139 results