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Machine learning for classification of hypertension subtypes using multi-omics: A multi-centre, retrospective, data-driven study.
Reel PS, Reel S, van Kralingen JC, Langton K, Lang K, Erlic Z, Larsen CK, Amar L, Pamporaki C, Mulatero P, Blanchard A, Kabat M, Robertson S, MacKenzie SM, Taylor AE, Peitzsch M, Ceccato F, Scaroni C, Reincke M, Kroiss M, Dennedy MC, Pecori A, Monticone S, Deinum J, Rossi GP, Lenzini L, McClure JD, Nind T, Riddell A, Stell A, Cole C, Sudano I, Prehn C, Adamski J, Gimenez-Roqueplo AP, Assié G, Arlt W, Beuschlein F, Eisenhofer G, Davies E, Zennaro MC, Jefferson E. Reel PS, et al. Among authors: arlt w. EBioMedicine. 2022 Oct;84:104276. doi: 10.1016/j.ebiom.2022.104276. Epub 2022 Sep 27. EBioMedicine. 2022. PMID: 36179553 Free PMC article.
Mitotane therapy in adrenocortical cancer induces CYP3A4 and inhibits 5α-reductase, explaining the need for personalized glucocorticoid and androgen replacement.
Chortis V, Taylor AE, Schneider P, Tomlinson JW, Hughes BA, O'Neil DM, Libé R, Allolio B, Bertagna X, Bertherat J, Beuschlein F, Fassnacht M, Karavitaki N, Mannelli M, Mantero F, Opocher G, Porfiri E, Quinkler M, Sherlock M, Terzolo M, Nightingale P, Shackleton CH, Stewart PM, Hahner S, Arlt W. Chortis V, et al. Among authors: arlt w. J Clin Endocrinol Metab. 2013 Jan;98(1):161-71. doi: 10.1210/jc.2012-2851. Epub 2012 Nov 16. J Clin Endocrinol Metab. 2013. PMID: 23162091 Free article. Clinical Trial.
Analysis of plasma 3-methoxytyramine, normetanephrine and metanephrine by ultraperformance liquid chromatography-tandem mass spectrometry: utility for diagnosis of dopamine-producing metastatic phaeochromocytoma.
Peitzsch M, Prejbisz A, Kroiß M, Beuschlein F, Arlt W, Januszewicz A, Siegert G, Eisenhofer G. Peitzsch M, et al. Among authors: arlt w. Ann Clin Biochem. 2013 Mar;50(Pt 2):147-55. doi: 10.1258/acb.2012.012112. Ann Clin Biochem. 2013. PMID: 23512172
Steroid metabolome analysis reveals prevalent glucocorticoid excess in primary aldosteronism.
Arlt W, Lang K, Sitch AJ, Dietz AS, Rhayem Y, Bancos I, Feuchtinger A, Chortis V, Gilligan LC, Ludwig P, Riester A, Asbach E, Hughes BA, O'Neil DM, Bidlingmaier M, Tomlinson JW, Hassan-Smith ZK, Rees DA, Adolf C, Hahner S, Quinkler M, Dekkers T, Deinum J, Biehl M, Keevil BG, Shackleton CH, Deeks JJ, Walch AK, Beuschlein F, Reincke M. Arlt W, et al. JCI Insight. 2017 Apr 20;2(8):e93136. doi: 10.1172/jci.insight.93136. eCollection 2017 Apr 20. JCI Insight. 2017. PMID: 28422753 Free PMC article.
378 results