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Efficacy and safety of setmelanotide, an MC4R agonist, in individuals with severe obesity due to LEPR or POMC deficiency: single-arm, open-label, multicentre, phase 3 trials.
Clément K, van den Akker E, Argente J, Bahm A, Chung WK, Connors H, De Waele K, Farooqi IS, Gonneau-Lejeune J, Gordon G, Kohlsdorf K, Poitou C, Puder L, Swain J, Stewart M, Yuan G, Wabitsch M, Kühnen P; Setmelanotide POMC and LEPR Phase 3 Trial Investigators. Clément K, et al. Among authors: argente j. Lancet Diabetes Endocrinol. 2020 Dec;8(12):960-970. doi: 10.1016/S2213-8587(20)30364-8. Epub 2020 Oct 30. Lancet Diabetes Endocrinol. 2020. PMID: 33137293 Clinical Trial.
Molecular basis of human obesity.
Martos-Moreno GA, Argente J. Martos-Moreno GA, et al. Among authors: argente j. J Pediatr Endocrinol Metab. 2005 Dec;18 Suppl 1:1187-97. doi: 10.1515/JPEM.2005.18.s1.1187. J Pediatr Endocrinol Metab. 2005. PMID: 16398449 Review. No abstract available.
Primary acid-labile subunit deficiency due to recessive IGFALS mutations results in postnatal growth deficit associated with low circulating insulin growth factor (IGF)-I, IGF binding protein-3 levels, and hyperinsulinemia.
Heath KE, Argente J, Barrios V, Pozo J, Díaz-González F, Martos-Moreno GA, Caimari M, Gracia R, Campos-Barros A. Heath KE, et al. Among authors: argente j. J Clin Endocrinol Metab. 2008 May;93(5):1616-24. doi: 10.1210/jc.2007-2678. Epub 2008 Feb 26. J Clin Endocrinol Metab. 2008. PMID: 18303074
Effect of weight loss on high-molecular weight adiponectin in obese children.
Martos-Moreno GÁ, Barrios V, Martínez G, Hawkins F, Argente J. Martos-Moreno GÁ, et al. Among authors: argente j. Obesity (Silver Spring). 2010 Dec;18(12):2288-94. doi: 10.1038/oby.2010.68. Epub 2010 Mar 25. Obesity (Silver Spring). 2010. PMID: 20339359 Free article. Clinical Trial.
421 results