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Synthesis, in vitro and in vivo giardicidal activity of nitrothiazole-NSAID chimeras displaying broad antiprotozoal spectrum.
Colín-Lozano B, León-Rivera I, Chan-Bacab MJ, Ortega-Morales BO, Moo-Puc R, López-Guerrero V, Hernández-Núñez E, Argüello-Garcia R, Scior T, Barbosa-Cabrera E, Navarrete-Vázquez G. Colín-Lozano B, et al. Bioorg Med Chem Lett. 2017 Aug 1;27(15):3490-3494. doi: 10.1016/j.bmcl.2017.05.071. Epub 2017 May 24. Bioorg Med Chem Lett. 2017. PMID: 28645659
Activity of Thioallyl Compounds From Garlic Against Giardia duodenalis Trophozoites and in Experimental Giardiasis.
Argüello-García R, de la Vega-Arnaud M, Loredo-Rodríguez IJ, Mejía-Corona AM, Melgarejo-Trejo E, Espinoza-Contreras EA, Fonseca-Liñán R, González-Robles A, Pérez-Hernández N, Ortega-Pierres MG. Argüello-García R, et al. Front Cell Infect Microbiol. 2018 Oct 15;8:353. doi: 10.3389/fcimb.2018.00353. eCollection 2018. Front Cell Infect Microbiol. 2018. PMID: 30374433 Free PMC article.
Giardia duodenalis enolase is secreted as monomer during trophozoite-epithelial cell interactions, activates plasminogen and induces necroptotic damage.
Barroeta-Echegaray E, Fonseca-Liñán R, Argüello-García R, Rodríguez-Muñoz R, Bermúdez-Cruz RM, Nava P, Ortega-Pierres MG. Barroeta-Echegaray E, et al. Among authors: arguello garcia r. Front Cell Infect Microbiol. 2022 Aug 25;12:928687. doi: 10.3389/fcimb.2022.928687. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 36093180 Free PMC article.
Giardipain-1, a protease secreted by Giardia duodenalis trophozoites, causes junctional, barrier and apoptotic damage in epithelial cell monolayers.
Ortega-Pierres G, Argüello-García R, Laredo-Cisneros MS, Fonseca-Linán R, Gómez-Mondragón M, Inzunza-Arroyo R, Flores-Benítez D, Raya-Sandino A, Chavez-Munguía B, Ventura-Gallegos JL, Zentella-Dehesa A, Bermúdez-Cruz RM, González-Mariscal L. Ortega-Pierres G, et al. Int J Parasitol. 2018 Jul;48(8):621-639. doi: 10.1016/j.ijpara.2018.01.006. Epub 2018 Mar 21. Int J Parasitol. 2018. PMID: 29571981
41 results