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Tuning sterol extraction kinetics yields a renal-sparing polyene antifungal.
Maji A, Soutar CP, Zhang J, Lewandowska A, Uno BE, Yan S, Shelke Y, Murhade G, Nimerovsky E, Borcik CG, Arango AS, Lange JD, Marin-Toledo JP, Lyu Y, Bailey KL, Roady PJ, Holler JT, Khandelwal A, SantaMaria AM, Sanchez H, Juvvadi PR, Johns G, Hageman MJ, Krise J, Gebremariam T, Youssef EG, Bartizal K, Marr KA, Steinbach WJ, Ibrahim AS, Patterson TF, Wiederhold NP, Andes DR, Pogorelov TV, Schwieters CD, Fan TM, Rienstra CM, Burke MD. Maji A, et al. Among authors: arango as. Nature. 2023 Nov;623(7989):1079-1085. doi: 10.1038/s41586-023-06710-4. Epub 2023 Nov 8. Nature. 2023. PMID: 37938782 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 36783126
Anthracycline derivatives inhibit cardiac CYP2J2.
Kim JS, Arango AS, Shah S, Arnold WR, Tajkhorshid E, Das A. Kim JS, et al. Among authors: arango as. J Inorg Biochem. 2022 Apr;229:111722. doi: 10.1016/j.jinorgbio.2022.111722. Epub 2022 Jan 13. J Inorg Biochem. 2022. PMID: 35078036 Free PMC article.
A small-molecule competitive inhibitor of phosphatidic acid binding by the AAA+ protein NSF/Sec18 blocks the SNARE-priming stage of vacuole fusion.
Sparks RP, Arango AS, Starr ML, Aboff ZL, Hurst LR, Rivera-Kohr DA, Zhang C, Harnden KA, Jenkins JL, Guida WC, Tajkhorshid E, Fratti RA. Sparks RP, et al. Among authors: arango as. J Biol Chem. 2019 Nov 15;294(46):17168-17185. doi: 10.1074/jbc.RA119.008865. Epub 2019 Sep 12. J Biol Chem. 2019. PMID: 31515268 Free PMC article.
15 results