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MAPK, beta-amyloid and synaptic dysfunction: the role of RAGE.
Origlia N, Arancio O, Domenici L, Yan SS. Origlia N, et al. Among authors: arancio o. Expert Rev Neurother. 2009 Nov;9(11):1635-45. doi: 10.1586/ern.09.107. Expert Rev Neurother. 2009. PMID: 19903023 Free PMC article. Review.
ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease.
Lustbader JW, Cirilli M, Lin C, Xu HW, Takuma K, Wang N, Caspersen C, Chen X, Pollak S, Chaney M, Trinchese F, Liu S, Gunn-Moore F, Lue LF, Walker DG, Kuppusamy P, Zewier ZL, Arancio O, Stern D, Yan SS, Wu H. Lustbader JW, et al. Among authors: arancio o. Science. 2004 Apr 16;304(5669):448-52. doi: 10.1126/science.1091230. Science. 2004. PMID: 15087549
Receptor for advanced glycation end product-dependent activation of p38 mitogen-activated protein kinase contributes to amyloid-beta-mediated cortical synaptic dysfunction.
Origlia N, Righi M, Capsoni S, Cattaneo A, Fang F, Stern DM, Chen JX, Schmidt AM, Arancio O, Yan SD, Domenici L. Origlia N, et al. Among authors: arancio o. J Neurosci. 2008 Mar 26;28(13):3521-30. doi: 10.1523/JNEUROSCI.0204-08.2008. J Neurosci. 2008. PMID: 18367618 Free PMC article.
Inhibition of amyloid-beta (Abeta) peptide-binding alcohol dehydrogenase-Abeta interaction reduces Abeta accumulation and improves mitochondrial function in a mouse model of Alzheimer's disease.
Yao J, Du H, Yan S, Fang F, Wang C, Lue LF, Guo L, Chen D, Stern DM, Gunn Moore FJ, Xi Chen J, Arancio O, Yan SS. Yao J, et al. Among authors: arancio o. J Neurosci. 2011 Feb 9;31(6):2313-20. doi: 10.1523/JNEUROSCI.4717-10.2011. J Neurosci. 2011. PMID: 21307267 Free PMC article.
Increased neuronal PreP activity reduces Aβ accumulation, attenuates neuroinflammation and improves mitochondrial and synaptic function in Alzheimer disease's mouse model.
Fang D, Wang Y, Zhang Z, Du H, Yan S, Sun Q, Zhong C, Wu L, Vangavaragu JR, Yan S, Hu G, Guo L, Rabinowitz M, Glaser E, Arancio O, Sosunov AA, McKhann GM, Chen JX, Yan SS. Fang D, et al. Among authors: arancio o. Hum Mol Genet. 2015 Sep 15;24(18):5198-210. doi: 10.1093/hmg/ddv241. Epub 2015 Jun 29. Hum Mol Genet. 2015. PMID: 26123488 Free PMC article.
206 results