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Ligand modulation of sidechain dynamics in a wild-type human GPCR.
Clark LD, Dikiy I, Chapman K, Rödström KE, Aramini J, LeVine MV, Khelashvili G, Rasmussen SG, Gardner KH, Rosenbaum DM. Clark LD, et al. Elife. 2017 Oct 6;6:e28505. doi: 10.7554/eLife.28505. Elife. 2017. PMID: 28984574 Free PMC article.
Unraveling the Mechanism of a LOV Domain Optogenetic Sensor: A Glutamine Lever Induces Unfolding of the Jα Helix.
Iuliano JN, Collado JT, Gil AA, Ravindran PT, Lukacs A, Shin S, Woroniecka HA, Adamczyk K, Aramini JM, Edupuganti UR, Hall CR, Greetham GM, Sazanovich IV, Clark IP, Daryaee T, Toettcher JE, French JB, Gardner KH, Simmerling CL, Meech SR, Tonge PJ. Iuliano JN, et al. Among authors: aramini jm. ACS Chem Biol. 2020 Oct 16;15(10):2752-2765. doi: 10.1021/acschembio.0c00543. Epub 2020 Sep 18. ACS Chem Biol. 2020. PMID: 32880430 Free PMC article.
Preparation of protein samples for NMR structure, function, and small-molecule screening studies.
Acton TB, Xiao R, Anderson S, Aramini J, Buchwald WA, Ciccosanti C, Conover K, Everett J, Hamilton K, Huang YJ, Janjua H, Kornhaber G, Lau J, Lee DY, Liu G, Maglaqui M, Ma L, Mao L, Patel D, Rossi P, Sahdev S, Shastry R, Swapna GV, Tang Y, Tong S, Wang D, Wang H, Zhao L, Montelione GT. Acton TB, et al. Methods Enzymol. 2011;493:21-60. doi: 10.1016/B978-0-12-381274-2.00002-9. Methods Enzymol. 2011. PMID: 21371586 Free PMC article.
Comparisons of NMR spectral quality and success in crystallization demonstrate that NMR and X-ray crystallography are complementary methods for small protein structure determination.
Snyder DA, Chen Y, Denissova NG, Acton T, Aramini JM, Ciano M, Karlin R, Liu J, Manor P, Rajan PA, Rossi P, Swapna GV, Xiao R, Rost B, Hunt J, Montelione GT. Snyder DA, et al. Among authors: aramini jm. J Am Chem Soc. 2005 Nov 30;127(47):16505-11. doi: 10.1021/ja053564h. J Am Chem Soc. 2005. PMID: 16305237
A microscale protein NMR sample screening pipeline.
Rossi P, Swapna GV, Huang YJ, Aramini JM, Anklin C, Conover K, Hamilton K, Xiao R, Acton TB, Ertekin A, Everett JK, Montelione GT. Rossi P, et al. Among authors: aramini jm. J Biomol NMR. 2010 Jan;46(1):11-22. doi: 10.1007/s10858-009-9386-z. Epub 2009 Nov 14. J Biomol NMR. 2010. PMID: 19915800 Free PMC article.
85 results