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The role of C5a-C5aR1 axis in bone pathophysiology: A mini-review.
Ruocco A, Sirico A, Novelli R, Iannelli S, Van Breda SV, Kyburz D, Hasler P, Aramini A, Amendola PG. Ruocco A, et al. Among authors: aramini a. Front Cell Dev Biol. 2022 Aug 8;10:957800. doi: 10.3389/fcell.2022.957800. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 36003145 Free PMC article. Review.
Unexpected Salt/Cocrystal Polymorphism of the Ketoprofen-Lysine System: Discovery of a New Ketoprofen-l-Lysine Salt Polymorph with Different Physicochemical and Pharmacokinetic Properties.
Aramini A, Bianchini G, Lillini S, Bordignon S, Tomassetti M, Novelli R, Mattioli S, Lvova L, Paolesse R, Chierotti MR, Allegretti M. Aramini A, et al. Pharmaceuticals (Basel). 2021 Jun 10;14(6):555. doi: 10.3390/ph14060555. Pharmaceuticals (Basel). 2021. PMID: 34200917 Free PMC article.
Inflammation-Independent Antinociceptive Effects of DF2755A, a CXCR1/2 Selective Inhibitor: A New Potential Therapeutic Treatment for Peripheral Neuropathy Associated to Non-Ulcerative Interstitial Cystitis/Bladder Pain Syndrome.
Brandolini L, Aramini A, Bianchini G, Ruocco A, Bertini R, Novelli R, Angelico P, Valsecchi AE, Russo R, Castelli V, Cimini A, Allegretti M. Brandolini L, et al. Among authors: aramini a. Front Pharmacol. 2022 Apr 28;13:854238. doi: 10.3389/fphar.2022.854238. eCollection 2022. Front Pharmacol. 2022. PMID: 35571079 Free PMC article.
Paclitaxel binds and activates C5aR1: A new potential therapeutic target for the prevention of chemotherapy-induced peripheral neuropathy and hypersensitivity reactions.
Brandolini L, d'Angelo M, Novelli R, Castelli V, Giorgio C, Sirico A, Cocchiaro P, D'Egidio F, Benedetti E, Cristiano C, Bugatti A, Ruocco A, Amendola PG, Talarico C, Manelfi C, Iaconis D, Beccari A, Quadros AU, Cunha TM, Caruso A, Russo R, Cimini A, Aramini A, Allegretti M. Brandolini L, et al. Among authors: aramini a. Cell Death Dis. 2022 May 25;13(5):500. doi: 10.1038/s41419-022-04964-w. Cell Death Dis. 2022. PMID: 35614037 Free PMC article.
Ketoprofen lysine salt has a better gastrointestinal and renal tolerability than ketoprofen acid: A comparative tolerability study in the Beagle dog.
Novelli R, Aramini A, Boccella S, Bagnasco M, Cattani F, Ferrari MP, Goisis G, Minnella EM, Allegretti M, Pace V. Novelli R, et al. Among authors: aramini a. Biomed Pharmacother. 2022 Sep;153:113336. doi: 10.1016/j.biopha.2022.113336. Epub 2022 Jun 27. Biomed Pharmacother. 2022. PMID: 35772374 Free article.
CXCR1/2 dual-inhibitor ladarixin reduces tumour burden and promotes immunotherapy response in pancreatic cancer.
Piro G, Carbone C, Agostini A, Esposito A, De Pizzol M, Novelli R, Allegretti M, Aramini A, Caggiano A, Granitto A, De Sanctis F, Ugel S, Corbo V, Martini M, Lawlor RT, Scarpa A, Tortora G. Piro G, et al. Among authors: aramini a. Br J Cancer. 2023 Jan;128(2):331-341. doi: 10.1038/s41416-022-02028-6. Epub 2022 Nov 16. Br J Cancer. 2023. PMID: 36385556 Free PMC article.
Ketoprofen, lysine and gabapentin co-crystal magnifies synergistic efficacy and tolerability of the constituent drugs: Pre-clinical evidences towards an innovative therapeutic approach for neuroinflammatory pain.
Aramini A, Bianchini G, Lillini S, Tomassetti M, Pacchiarotti N, Canestrari D, Cocchiaro P, Novelli R, Dragani MC, Palmerio F, Mattioli S, Bordignon S, d'Angelo M, Castelli V, d'Egidio F, Maione S, Luongo L, Boccella S, Cimini A, Brandolini L, Chierotti MR, Allegretti M. Aramini A, et al. Biomed Pharmacother. 2023 Jul;163:114845. doi: 10.1016/j.biopha.2023.114845. Epub 2023 May 9. Biomed Pharmacother. 2023. PMID: 37167730 Free article.
The therapeutic potential of an allosteric non-competitive CXCR1/2 antagonist for diabetic nephropathy.
Grasselli C, Bombelli S, D'Esposito V, Di Tolla MF, L'Imperio V, Rocchio F, Miscione MS, Formisano P, Pagni F, Novelli R, Ruffini PA, Aramini A, Allegretti M, Perego R, De Filippis L. Grasselli C, et al. Among authors: aramini a. Diabetes Metab Res Rev. 2023 Oct;39(7):e3694. doi: 10.1002/dmrr.3694. Epub 2023 Jul 20. Diabetes Metab Res Rev. 2023. PMID: 37470287
44 results