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The lipidomic and inflammatory profiles of visceral and subcutaneous adipose tissues are distinctly regulated by the SGLT2 inhibitor empagliflozin in Zucker diabetic fatty rats.
Aragón-Herrera A, Moraña-Fernández S, Otero-Santiago M, Anido-Varela L, Campos-Toimil M, García-Seara J, Román A, Seijas J, García-Caballero L, Rodríguez J, Tarazón E, Roselló-Lletí E, Portolés M, Lage R, Gualillo O, González-Juanatey JR, Feijóo-Bandín S, Lago F. Aragón-Herrera A, et al. Biomed Pharmacother. 2023 May;161:114535. doi: 10.1016/j.biopha.2023.114535. Epub 2023 Mar 15. Biomed Pharmacother. 2023. PMID: 36931025 Free article.
Metabolic alterations derived from absence of Two-Pore Channel 1 at cardiac level.
Garcia-Rua V, Feijoo-Bandin S, Garcia-Vence M, Aragon-Herrera A, Bravo SB, Rodriguez-Penas D, Mosquera-Leal A, Lear PV, Parrington J, Alonso J, Rosello-Lleti E, Portoles M, Rivera M, Gonzalez-Juanatey JR, Lago F. Garcia-Rua V, et al. J Biosci. 2016 Dec;41(4):643-658. doi: 10.1007/s12038-016-9647-4. J Biosci. 2016. PMID: 27966485
Relaxin-2 in Cardiometabolic Diseases: Mechanisms of Action and Future Perspectives.
Feijóo-Bandín S, Aragón-Herrera A, Rodríguez-Penas D, Portolés M, Roselló-Lletí E, Rivera M, González-Juanatey JR, Lago F. Feijóo-Bandín S, et al. Front Physiol. 2017 Aug 18;8:599. doi: 10.3389/fphys.2017.00599. eCollection 2017. Front Physiol. 2017. PMID: 28868039 Free PMC article. Review.
Serelaxin (recombinant human relaxin-2) treatment affects the endogenous synthesis of long chain poly-unsaturated fatty acids and induces substantial alterations of lipidome and metabolome profiles in rat cardiac tissue.
Aragón-Herrera A, Feijóo-Bandín S, Abella V, Álvarez L, Roselló-Lletí E, Portolés M, Tarazón E, Bigazzi M, Bani D, Gualillo O, González-Juanatey JR, Lago F. Aragón-Herrera A, et al. Pharmacol Res. 2019 Jun;144:51-65. doi: 10.1016/j.phrs.2019.04.009. Epub 2019 Apr 5. Pharmacol Res. 2019. PMID: 30954631
Empagliflozin reduces the levels of CD36 and cardiotoxic lipids while improving autophagy in the hearts of Zucker diabetic fatty rats.
Aragón-Herrera A, Feijóo-Bandín S, Otero Santiago M, Barral L, Campos-Toimil M, Gil-Longo J, Costa Pereira TM, García-Caballero T, Rodríguez-Segade S, Rodríguez J, Tarazón E, Roselló-Lletí E, Portolés M, Gualillo O, González-Juanatey JR, Lago F. Aragón-Herrera A, et al. Biochem Pharmacol. 2019 Dec;170:113677. doi: 10.1016/j.bcp.2019.113677. Epub 2019 Oct 21. Biochem Pharmacol. 2019. PMID: 31647926
Adipokines and Inflammation: Focus on Cardiovascular Diseases.
Feijóo-Bandín S, Aragón-Herrera A, Moraña-Fernández S, Anido-Varela L, Tarazón E, Roselló-Lletí E, Portolés M, Moscoso I, Gualillo O, González-Juanatey JR, Lago F. Feijóo-Bandín S, et al. Int J Mol Sci. 2020 Oct 18;21(20):7711. doi: 10.3390/ijms21207711. Int J Mol Sci. 2020. PMID: 33081064 Free PMC article. Review.
Relaxin has beneficial effects on liver lipidome and metabolic enzymes.
Aragón-Herrera A, Feijóo-Bandín S, Moraña-Fernández S, Anido-Varela L, Roselló-Lletí E, Portolés M, Tarazón E, Lage R, Moscoso I, Barral L, Bani D, Bigazzi M, Gualillo O, González-Juanatey JR, Lago F. Aragón-Herrera A, et al. FASEB J. 2021 Jul;35(7):e21737. doi: 10.1096/fj.202002620RR. FASEB J. 2021. PMID: 34143495
The Treatment With the SGLT2 Inhibitor Empagliflozin Modifies the Hepatic Metabolome of Male Zucker Diabetic Fatty Rats Towards a Protective Profile.
Aragón-Herrera A, Otero-Santiago M, Anido-Varela L, Moraña-Fernández S, Campos-Toimil M, García-Caballero T, Barral L, Tarazón E, Roselló-Lletí E, Portolés M, Gualillo O, Moscoso I, Lage R, González-Juanatey JR, Feijóo-Bandín S, Lago F. Aragón-Herrera A, et al. Front Pharmacol. 2022 Feb 2;13:827033. doi: 10.3389/fphar.2022.827033. eCollection 2022. Front Pharmacol. 2022. PMID: 35185578 Free PMC article.
Role of Sodium-Glucose Co-Transporter 2 Inhibitors in the Regulation of Inflammatory Processes in Animal Models.
Feijóo-Bandín S, Aragón-Herrera A, Otero-Santiago M, Anido-Varela L, Moraña-Fernández S, Tarazón E, Roselló-Lletí E, Portolés M, Gualillo O, González-Juanatey JR, Lago F. Feijóo-Bandín S, et al. Among authors: aragon herrera a. Int J Mol Sci. 2022 May 18;23(10):5634. doi: 10.3390/ijms23105634. Int J Mol Sci. 2022. PMID: 35628443 Free PMC article. Review.
18 results