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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1969 1
1980 1
1981 1
1982 3
1983 1
1984 4
1985 3
1986 3
1987 2
1988 1
1989 5
1990 5
1991 2
1992 8
1993 8
1994 10
1995 6
1996 8
1997 8
1998 10
1999 5
2000 4
2001 6
2002 5
2003 4
2004 3
2005 3
2006 9
2007 16
2008 11
2009 9
2010 8
2011 10
2012 6
2013 2
2014 2
2015 1
2016 5
2017 8
2018 5
2019 9
2020 11
2021 4
2022 7
2023 6
2024 1

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234 results

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Page 1
Neurotoxicity Associated with Treatment of Acute Lymphoblastic Leukemia Chemotherapy and Immunotherapy.
Śliwa-Tytko P, Kaczmarska A, Lejman M, Zawitkowska J. Śliwa-Tytko P, et al. Int J Mol Sci. 2022 May 15;23(10):5515. doi: 10.3390/ijms23105515. Int J Mol Sci. 2022. PMID: 35628334 Free PMC article. Review.
The most neurotoxical chemotherapeutics are L-asparaginase (L-ASP), methotrexate (MTX), vincristine (VCR), and nelarabine (Ara-G). Neurotoxicity associated with methotrexate (MTX-NT) occurs in 3-7% of children treated for ALL and is characterized by seizures, stroke …
The most neurotoxical chemotherapeutics are L-asparaginase (L-ASP), methotrexate (MTX), vincristine (VCR), and nelarabine (Ara-G …
Nelarabine.
Sanford M, Lyseng-Williamson KA. Sanford M, et al. Drugs. 2008;68(4):439-47. doi: 10.2165/00003495-200868040-00004. Drugs. 2008. PMID: 18318562 Review.
Nelarabine is an anticancer prodrug of arabinofuranosylguanine (ara-G), which is metabolized in cells to the cytotoxic metabolite ara-G triphosphate (ara-GTP). ...
Nelarabine is an anticancer prodrug of arabinofuranosylguanine (ara-G), which is metabolized in cells to the cytotoxic metabol …
Hyper-CVAD plus nelarabine in newly diagnosed adult T-cell acute lymphoblastic leukemia and T-lymphoblastic lymphoma.
Abaza Y, M Kantarjian H, Faderl S, Jabbour E, Jain N, Thomas D, Kadia T, Borthakur G, D Khoury J, Burger J, Wierda W, O'Brien S, Konopleva M, Ferrajoli A, Kebriaei P, Dabaja B, Kornblau S, Alvarado Y, Daver N, Pemmaraju N, Bose P, Thompson P, Al Azzawi H, Kelly M, Garris R, Jain P, Garcia-Manero G, Cortes J, Ravandi F. Abaza Y, et al. Am J Hematol. 2018 Jan;93(1):91-99. doi: 10.1002/ajh.24947. Epub 2017 Nov 3. Am J Hematol. 2018. PMID: 29047158 Free article.
Nelarabine, a water soluble prodrug of 9-beta-D-arabinofuranosylguanine (ara-G), is a T-cell specific purine nucleoside analogue. Given its activity in relapsed and refractory T acute lymphoblastic leukemia (T-ALL) and T lymphoblastic lymphoma (T-LBL), we sought to …
Nelarabine, a water soluble prodrug of 9-beta-D-arabinofuranosylguanine (ara-G), is a T-cell specific purine nucleoside analog …
In vitro efficacy of forodesine and nelarabine (ara-G) in pediatric leukemia.
Homminga I, Zwaan CM, Manz CY, Parker C, Bantia S, Smits WK, Higginbotham F, Pieters R, Meijerink JP. Homminga I, et al. Blood. 2011 Aug 25;118(8):2184-90. doi: 10.1182/blood-2011-02-337840. Epub 2011 Jul 5. Blood. 2011. PMID: 21730354 Free article.
Forodesine and nelarabine (the pro-drug of ara-G) are 2 nucleoside analogues with promising anti-leukemic activity. ...The mRNA levels of the transporters ENT1 and ENT2 were higher in ara-G-sensitive than -resistant samples. We conclude that especially …
Forodesine and nelarabine (the pro-drug of ara-G) are 2 nucleoside analogues with promising anti-leukemic activity. ...The mRN …
Dietary ARA Improves COX Activity in Broodstock and Offspring Survival Fitness of a Model Organism (Medaka Oryzias latipes).
Kowalska A, Kamaszewski M, Czarnowska-Kujawska M, Podlasz P, Kowalski RK. Kowalska A, et al. Animals (Basel). 2020 Nov 21;10(11):2174. doi: 10.3390/ani10112174. Animals (Basel). 2020. PMID: 33233393 Free PMC article.
A 3-week feeding trial was conducted in medaka broodstock (age five months) to examine the effect of dietary arachidonic acid (ARA) level (range: 4-23 mg g(-1) of total fatty acids (TFAs)) on fertility, cyclooxygenase (COX) activity, egg size, sperm motility parameters, hatching …
A 3-week feeding trial was conducted in medaka broodstock (age five months) to examine the effect of dietary arachidonic acid (ARA) level (r …
Nelarabine: a nucleoside analog with efficacy in T-cell and other leukemias.
Kisor DF. Kisor DF. Ann Pharmacother. 2005 Jun;39(6):1056-63. doi: 10.1345/aph.1E453. Epub 2005 May 3. Ann Pharmacother. 2005. PMID: 15870141 Review.
DATA SYNTHESIS: Nelarabine is the water-soluble, 6-methoxy analog of 9-beta-D-ara-G. Nelarabine is readily converted to ara-G by endogenous adenosine deaminase. The half-life of nelarabine is approximately 15 minutes compared with 2-4 hours for ara …
DATA SYNTHESIS: Nelarabine is the water-soluble, 6-methoxy analog of 9-beta-D-ara-G. Nelarabine is readily converted to ara …
Strengthening dengue control in Pakistan.
Saleem M, Sheikh A, Nawaz H, Ara G. Saleem M, et al. East Mediterr Health J. 2023 Dec 21;29(12):921-923. doi: 10.26719/emhj.23.099. East Mediterr Health J. 2023. PMID: 38279860 Free article. No abstract available.
Monkeypox virus: A potential pandemic?
Tarique D, Siddiqui AA, Ara G. Tarique D, et al. J Pak Med Assoc. 2023 Feb;73(2):460-461. doi: 10.47391/JPMA.7224. J Pak Med Assoc. 2023. PMID: 36800762 Free article. No abstract available.
Nelarabine in the treatment of pediatric and adult patients with T-cell acute lymphoblastic leukemia and lymphoma.
Kadia TM, Gandhi V. Kadia TM, et al. Expert Rev Hematol. 2017 Jan;10(1):1-8. doi: 10.1080/17474086.2017.1262757. Epub 2016 Dec 8. Expert Rev Hematol. 2017. PMID: 27869523 Free PMC article. Review.
Based on observations in patients with purine nucleoside phosphorylase (PNP) deficiency, a guanosine nucleoside analogue, arabinosylguanine (ara-G) was developed that provided T-cell specificity. Nelarabine was developed as the water-soluble, clinically useful-prodr …
Based on observations in patients with purine nucleoside phosphorylase (PNP) deficiency, a guanosine nucleoside analogue, arabinosylguanine …
Marine Anticancer Agents: An Overview with a Particular Focus on Their Chemical Classes.
Barreca M, Spanò V, Montalbano A, Cueto M, Díaz Marrero AR, Deniz I, Erdoğan A, Lukić Bilela L, Moulin C, Taffin-de-Givenchy E, Spriano F, Perale G, Mehiri M, Rotter A, P Thomas O, Barraja P, Gaudêncio SP, Bertoni F. Barreca M, et al. Mar Drugs. 2020 Dec 4;18(12):619. doi: 10.3390/md18120619. Mar Drugs. 2020. PMID: 33291602 Free PMC article. Review.
Marine-based pharmaceuticals have started to impact modern pharmacology and different anti-cancer drugs derived from marine compounds have been approved for clinical use, such as: cytarabine, vidarabine, nelarabine (prodrug of ara-G), fludarabine phosphate (pro-drug …
Marine-based pharmaceuticals have started to impact modern pharmacology and different anti-cancer drugs derived from marine compounds have b …
234 results