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In-depth mechanistic analysis including high-throughput RNA sequencing in the prediction of functional and structural cardiotoxicants using hiPSC cardiomyocytes.
Expert Opin Drug Metab Toxicol. 2023 Nov 23:1-23. doi: 10.1080/17425255.2023.2273378. Online ahead of print.
Expert Opin Drug Metab Toxicol. 2023.
PMID: 37995132
The RNA helicase Dbp7 promotes domain V/VI compaction and stabilization of inter-domain interactions during early 60S assembly.
Aquino GRR, Hackert P, Krogh N, Pan KT, Jaafar M, Henras AK, Nielsen H, Urlaub H, Bohnsack KE, Bohnsack MT.
Aquino GRR, et al.
Nat Commun. 2021 Oct 22;12(1):6152. doi: 10.1038/s41467-021-26208-9.
Nat Commun. 2021.
PMID: 34686661
Free PMC article.
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RNA helicase-mediated regulation of snoRNP dynamics on pre-ribosomes and rRNA 2'-O-methylation.
Aquino GRR, Krogh N, Hackert P, Martin R, Gallesio JD, van Nues RW, Schneider C, Watkins NJ, Nielsen H, Bohnsack KE, Bohnsack MT.
Aquino GRR, et al.
Nucleic Acids Res. 2021 Apr 19;49(7):4066-4084. doi: 10.1093/nar/gkab159.
Nucleic Acids Res. 2021.
PMID: 33721027
Free PMC article.
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RNA helicases mediate structural transitions and compositional changes in pre-ribosomal complexes.
Brüning L, Hackert P, Martin R, Davila Gallesio J, Aquino GRR, Urlaub H, Sloan KE, Bohnsack MT.
Brüning L, et al. Among authors: aquino grr.
Nat Commun. 2018 Dec 19;9(1):5383. doi: 10.1038/s41467-018-07783-w.
Nat Commun. 2018.
PMID: 30568249
Free PMC article.
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