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Electrophilic properties of itaconate and derivatives regulate the IκBζ-ATF3 inflammatory axis.
Bambouskova M, Gorvel L, Lampropoulou V, Sergushichev A, Loginicheva E, Johnson K, Korenfeld D, Mathyer ME, Kim H, Huang LH, Duncan D, Bregman H, Keskin A, Santeford A, Apte RS, Sehgal R, Johnson B, Amarasinghe GK, Soares MP, Satoh T, Akira S, Hai T, de Guzman Strong C, Auclair K, Roddy TP, Biller SA, Jovanovic M, Klechevsky E, Stewart KM, Randolph GJ, Artyomov MN. Bambouskova M, et al. Among authors: apte rs. Nature. 2018 Apr;556(7702):501-504. doi: 10.1038/s41586-018-0052-z. Epub 2018 Apr 18. Nature. 2018. PMID: 29670287 Free PMC article.
Endothelial cell FGF signaling is required for injury response but not for vascular homeostasis.
Oladipupo SS, Smith C, Santeford A, Park C, Sene A, Wiley LA, Osei-Owusu P, Hsu J, Zapata N, Liu F, Nakamura R, Lavine KJ, Blumer KJ, Choi K, Apte RS, Ornitz DM. Oladipupo SS, et al. Among authors: apte rs. Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):13379-84. doi: 10.1073/pnas.1324235111. Epub 2014 Aug 19. Proc Natl Acad Sci U S A. 2014. PMID: 25139991 Free PMC article.
Impaired autophagy in macrophages promotes inflammatory eye disease.
Santeford A, Wiley LA, Park S, Bamba S, Nakamura R, Gdoura A, Ferguson TA, Rao PK, Guan JL, Saitoh T, Akira S, Xavier R, Virgin HW 4th, Apte RS. Santeford A, et al. Among authors: apte rs. Autophagy. 2016 Oct 2;12(10):1876-1885. doi: 10.1080/15548627.2016.1207857. Epub 2016 Jul 27. Autophagy. 2016. PMID: 27463423 Free PMC article.
NAMPT-Mediated NAD(+) Biosynthesis Is Essential for Vision In Mice.
Lin JB, Kubota S, Ban N, Yoshida M, Santeford A, Sene A, Nakamura R, Zapata N, Kubota M, Tsubota K, Yoshino J, Imai SI, Apte RS. Lin JB, et al. Among authors: apte rs. Cell Rep. 2016 Sep 27;17(1):69-85. doi: 10.1016/j.celrep.2016.08.073. Cell Rep. 2016. PMID: 27681422 Free PMC article.
WNT7A/B promote choroidal neovascularization.
Lin JB, Sene A, Wiley LA, Santeford A, Nudleman E, Nakamura R, Lin JB, Moolani HV, Apte RS. Lin JB, et al. Among authors: apte rs. Exp Eye Res. 2018 Sep;174:107-112. doi: 10.1016/j.exer.2018.05.033. Epub 2018 Jun 1. Exp Eye Res. 2018. PMID: 29864439 Free PMC article.
180 results