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Salmonella manipulates the host to drive pathogenicity via induction of interleukin 1β.
Zigdon M, Sawaed J, Zelik L, Binyamin D, Ben-Simon S, Asulin N, Levin R, Modilevsky S, Naama M, Telpaz S, Rubin E, Awad A, Sawaed W, Harshuk-Shabso S, Nuriel-Ohayon M, Krishnamohan M, Werbner M, Koren O, Winter SE, Apte RN, Voronov E, Bel S. Zigdon M, et al. Among authors: apte rn. PLoS Biol. 2024 Jan 18;22(1):e3002486. doi: 10.1371/journal.pbio.3002486. eCollection 2024 Jan. PLoS Biol. 2024. PMID: 38236896 Free PMC article.
Tryptophol Acetate and Tyrosol Acetate, Small-Molecule Metabolites Identified in a Probiotic Mixture, Inhibit Hyperinflammation.
Malka O, Malishev R, Bersudsky M, Rajendran M, Krishnamohan M, Shaik J, Chamovitz DA, Tikhonov E, Sultan E, Koren O, Apte RN, Rosental B, Voronov E, Jelinek R. Malka O, et al. Among authors: apte rn. J Innate Immun. 2023;15(1):531-547. doi: 10.1159/000529782. Epub 2023 Feb 21. J Innate Immun. 2023. PMID: 36809756 Free PMC article.
Subcapsular Sinus Macrophages Promote Melanoma Metastasis to the Sentinel Lymph Nodes via an IL1α-STAT3 Axis.
Virgilio T, Bordini J, Cascione L, Sartori G, Latino I, Molina Romero D, Leoni C, Akhmedov M, Rinaldi A, Arribas AJ, Morone D, Seyed Jafari SM, Bersudsky M, Ottolenghi A, Kwee I, Chiaravalli AM, Sessa F, Hunger RE, Bruno A, Mortara L, Voronov E, Monticelli S, Apte RN, Bertoni F, Gonzalez SF. Virgilio T, et al. Among authors: apte rn. Cancer Immunol Res. 2022 Dec 2;10(12):1525-1541. doi: 10.1158/2326-6066.CIR-22-0225. Cancer Immunol Res. 2022. PMID: 36206577 Free PMC article.
Life-extended glycosylated IL-2 promotes Treg induction and suppression of autoimmunity.
Ottolenghi A, Bolel P, Sarkar R, Greenshpan Y, Iraqi M, Ghosh S, Bhattacharya B, Taylor ZV, Kundu K, Radinsky O, Gazit R, Stepensky D, Apte RN, Voronov E, Porgador A. Ottolenghi A, et al. Among authors: apte rn. Sci Rep. 2021 Apr 7;11(1):7676. doi: 10.1038/s41598-021-87102-4. Sci Rep. 2021. PMID: 33828163 Free PMC article.
Interleukin-1α dependent survival of cardiac fibroblasts is associated with StAR/STARD1 expression and improved cardiac remodeling and function after myocardial infarction.
Razin T, Melamed-Book N, Argaman J, Galin I, Lowy Y, Anuka E, Naftali-Shani N, Kandel-Kfir M, Garfinkel BP, Brielle S, Granot Z, Apte RN, Conway SJ, Molkentin JD, Kamari Y, Leor J, Orly J. Razin T, et al. Among authors: apte rn. J Mol Cell Cardiol. 2021 Jun;155:125-137. doi: 10.1016/j.yjmcc.2020.10.013. Epub 2020 Oct 30. J Mol Cell Cardiol. 2021. PMID: 33130150
One hits (almost) all.
Boraschi D, Apte RN, Martin MU. Boraschi D, et al. Among authors: apte rn. Nat Immunol. 2019 Sep;20(9):1095-1097. doi: 10.1038/s41590-019-0463-5. Nat Immunol. 2019. PMID: 31427774 No abstract available.
Proinflammatory Macrophages Promote Multiple Myeloma Resistance to Bortezomib Therapy.
Beyar-Katz O, Magidey K, Reiner-Benaim A, Barak N, Avivi I, Cohen Y, Timaner M, Avraham S, Hayun M, Lavi N, Bersudsky M, Voronov E, Apte RN, Shaked Y. Beyar-Katz O, et al. Among authors: apte rn. Mol Cancer Res. 2019 Nov;17(11):2331-2340. doi: 10.1158/1541-7786.MCR-19-0487. Epub 2019 Aug 13. Mol Cancer Res. 2019. PMID: 31409628
140 results