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Sphingosine Kinases Promote Ebola Virus Infection and Can Be Targeted to Inhibit Filoviruses, Coronaviruses, and Arenaviruses Using Late Endocytic Trafficking to Enter Cells.
ACS Infect Dis. 2023 May 12;9(5):1064-1077. doi: 10.1021/acsinfecdis.2c00416. Epub 2023 Apr 13.
ACS Infect Dis. 2023.
PMID: 37053583
Free PMC article.
Designing Dual Transglutaminase 2/Histone Deacetylase Inhibitors Effective at Halting Neuronal Death.
Basso M, Chen HH, Tripathy D, Conte M, Apperley KYP, De Simone A, Keillor JW, Ratan R, Nebbioso A, Sarno F, Altucci L, Milelli A.
Basso M, et al. Among authors: apperley kyp.
ChemMedChem. 2018 Feb 6;13(3):227-230. doi: 10.1002/cmdc.201700601. Epub 2018 Jan 18.
ChemMedChem. 2018.
PMID: 29286587
Item in Clipboard
Hydroxy-substituted trans-cinnamoyl derivatives as multifunctional tools in the context of Alzheimer's disease.
De Simone A, Bartolini M, Baschieri A, Apperley KYP, Chen HH, Guardigni M, Montanari S, Kobrlova T, Soukup O, Valgimigli L, Andrisano V, Keillor JW, Basso M, Milelli A.
De Simone A, et al. Among authors: apperley kyp.
Eur J Med Chem. 2017 Oct 20;139:378-389. doi: 10.1016/j.ejmech.2017.07.058. Epub 2017 Jul 25.
Eur J Med Chem. 2017.
PMID: 28810189
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Development of new scaffolds as reversible tissue transglutaminase inhibitors, with improved potency or resistance to glutathione addition.
Apperley KYP, Roy I, Saucier V, Brunet-Filion N, Piscopo SP, Pardin C, De Francesco É, Hao C, Keillor JW.
Apperley KYP, et al.
Medchemcomm. 2016 Dec 5;8(2):338-345. doi: 10.1039/c6md00565a. eCollection 2017 Feb 1.
Medchemcomm. 2016.
PMID: 30108749
Free PMC article.
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Transglutaminase inhibitors: a patent review.
Keillor JW, Apperley KY.
Keillor JW, et al. Among authors: apperley ky.
Expert Opin Ther Pat. 2016;26(1):49-63. doi: 10.1517/13543776.2016.1115836. Epub 2015 Nov 24.
Expert Opin Ther Pat. 2016.
PMID: 26560530
Review.
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Inhibitors of tissue transglutaminase.
Keillor JW, Apperley KY, Akbar A.
Keillor JW, et al. Among authors: apperley ky.
Trends Pharmacol Sci. 2015 Jan;36(1):32-40. doi: 10.1016/j.tips.2014.10.014. Epub 2014 Dec 12.
Trends Pharmacol Sci. 2015.
PMID: 25500711
Review.
Item in Clipboard
Acyl transfer mechanisms of tissue transglutaminase.
Keillor JW, Clouthier CM, Apperley KYP, Akbar A, Mulani A.
Keillor JW, et al. Among authors: apperley kyp.
Bioorg Chem. 2014 Dec;57:186-197. doi: 10.1016/j.bioorg.2014.06.003. Epub 2014 Jun 25.
Bioorg Chem. 2014.
PMID: 25035302
Review.
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