Appelman MD - Search Results

1

The Lipid Raft Component Stomatin Interacts with the Na⁺ Taurocholate Cotransporting Polypeptide (NTCP) and Modulates Bile Salt Uptake.

Appelman MD, Robin MJD, Vogels EWM, Wolzak C, Vos WG, Vos HR, Van Es RM, Burgering BMT, Van de Graaf SFJ. Appelman MD, et al. Cells. 2020 Apr 16;9(4):986. doi: 10.3390/cells9040986. Cells. 2020. PMID: 32316189 Free PMC article.

2

N-Glycosylation of the Na+-Taurocholate Cotransporting Polypeptide (NTCP) Determines Its Trafficking and Stability and Is Required for Hepatitis B Virus Infection.

Appelman MD, Chakraborty A, Protzer U, McKeating JA, van de Graaf SF. Appelman MD, et al. PLoS One. 2017 Jan 26;12(1):e0170419. doi: 10.1371/journal.pone.0170419. eCollection 2017. PLoS One. 2017. PMID: 28125599 Free PMC article.

3

Calnexin Depletion by Endoplasmic Reticulum Stress During Cholestasis Inhibits the Na⁺-Taurocholate Cotransporting Polypeptide.

Robin MJD, Appelman MD, Vos HR, van Es RM, Paton JC, Paton AW, Burgering B, Fickert P, Heijmans J, van de Graaf SFJ. Robin MJD, et al. Among authors: appelman md. Hepatol Commun. 2018 Oct 23;2(12):1550-1566. doi: 10.1002/hep4.1262. eCollection 2018 Dec. Hepatol Commun. 2018. PMID: 30556041 Free PMC article.

4

Molecular regulation of the hepatic bile acid uptake transporter and HBV entry receptor NTCP.

Appelman MD, Wettengel JM, Protzer U, Oude Elferink RPJ, van de Graaf SFJ. Appelman MD, et al. Biochim Biophys Acta Mol Cell Biol Lipids. 2021 Aug;1866(8):158960. doi: 10.1016/j.bbalip.2021.158960. Epub 2021 Apr 29. Biochim Biophys Acta Mol Cell Biol Lipids. 2021. PMID: 33932583 Free article. Review.

5

Mechanistic insights into the inhibition of NTCP by myrcludex B.

Donkers JM, Appelman MD, van de Graaf SFJ. Donkers JM, et al. Among authors: appelman md. JHEP Rep. 2019 Aug 1;1(4):278-285. doi: 10.1016/j.jhepr.2019.07.006. eCollection 2019 Oct. JHEP Rep. 2019. PMID: 32039379 Free PMC article.

6

Post-Translational Modifications of FXR; Implications for Cholestasis and Obesity-Related Disorders.

Appelman MD, van der Veen SW, van Mil SWC. Appelman MD, et al. Front Endocrinol (Lausanne). 2021 Sep 27;12:729828. doi: 10.3389/fendo.2021.729828. eCollection 2021. Front Endocrinol (Lausanne). 2021. PMID: 34646233 Free PMC article. Review.

7

Protein Condensation in the Nuclear Receptor Family; Implications for Transcriptional Output.

Appelman MD, Hollaar EE, Schuijers J, van Mil SWC. Appelman MD, et al. Adv Exp Med Biol. 2022;1390:243-253. doi: 10.1007/978-3-031-11836-4_14. Adv Exp Med Biol. 2022. PMID: 36107323

8

Development of an acid ceramidase activity-based probe.

Ouairy CM, Ferraz MJ, Boot RG, Baggelaar MP, van der Stelt M, Appelman M, van der Marel GA, Florea BI, Aerts JM, Overkleeft HS. Ouairy CM, et al. Chem Commun (Camb). 2015 Apr 11;51(28):6161-3. doi: 10.1039/c5cc00356c. Chem Commun (Camb). 2015. PMID: 25748248

9

Lysosomal glycosphingolipid catabolism by acid ceramidase: formation of glycosphingoid bases during deficiency of glycosidases.

Ferraz MJ, Marques AR, Appelman MD, Verhoek M, Strijland A, Mirzaian M, Scheij S, Ouairy CM, Lahav D, Wisse P, Overkleeft HS, Boot RG, Aerts JM. Ferraz MJ, et al. Among authors: appelman md. FEBS Lett. 2016 Mar;590(6):716-25. doi: 10.1002/1873-3468.12104. Epub 2016 Mar 3. FEBS Lett. 2016. PMID: 26898341 Free article.

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