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TP-0184 inhibits FLT3/ACVR1 to overcome FLT3 inhibitor resistance and hinder AML growth synergistically with venetoclax.
Tyagi A, Jaggupilli A, Ly S, Yuan B, El-Dana F, Hegde VL, Anand V, Kumar B, Puppala M, Yin Z, Wong STC, Mollard A, Vankayalapati H, Foulks JM, Warner SL, Daver N, Borthakur G, Battula VL. Tyagi A, et al. Among authors: jaggupilli a. Leukemia. 2024 Jan;38(1):82-95. doi: 10.1038/s41375-023-02086-6. Epub 2023 Nov 25. Leukemia. 2024. PMID: 38007585
Plasticity of the ligand binding pocket in the bitter taste receptor T2R7.
Liu K, Jaggupilli A, Premnath D, Chelikani P. Liu K, et al. Among authors: jaggupilli a. Biochim Biophys Acta Biomembr. 2018 May;1860(5):991-999. doi: 10.1016/j.bbamem.2018.01.014. Epub 2018 Feb 12. Biochim Biophys Acta Biomembr. 2018. PMID: 29355483 Free article.
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