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Unbiased identification of novel transcription factors in striatal compartmentation and striosome maturation.
Cirnaru MD, Song S, Tshilenge KT, Corwin C, Mleczko J, Galicia Aguirre C, Benlhabib H, Bendl J, Apontes P, Fullard J, Creus-Muncunill J, Reyahi A, Nik AM, Carlsson P, Roussos P, Mooney SD, Ellerby LM, Ehrlich ME. Cirnaru MD, et al. Among authors: apontes p. Elife. 2021 Oct 5;10:e65979. doi: 10.7554/eLife.65979. Elife. 2021. PMID: 34609283 Free PMC article.
The three-dimensional landscape of cortical chromatin accessibility in Alzheimer's disease.
Bendl J, Hauberg ME, Girdhar K, Im E, Vicari JM, Rahman S, Fernando MB, Townsley KG, Dong P, Misir R, Kleopoulos SP, Reach SM, Apontes P, Zeng B, Zhang W, Voloudakis G, Brennand KJ, Nixon RA, Haroutunian V, Hoffman GE, Fullard JF, Roussos P. Bendl J, et al. Among authors: apontes p. Nat Neurosci. 2022 Oct;25(10):1366-1378. doi: 10.1038/s41593-022-01166-7. Epub 2022 Sep 28. Nat Neurosci. 2022. PMID: 36171428 Free PMC article.
Population-level variation in enhancer expression identifies disease mechanisms in the human brain.
Dong P, Hoffman GE, Apontes P, Bendl J, Rahman S, Fernando MB, Zeng B, Vicari JM, Zhang W, Girdhar K, Townsley KG, Misir R; CommonMind Consortium; Brennand KJ, Haroutunian V, Voloudakis G, Fullard JF, Roussos P. Dong P, et al. Among authors: apontes p. Nat Genet. 2022 Oct;54(10):1493-1503. doi: 10.1038/s41588-022-01170-4. Epub 2022 Sep 26. Nat Genet. 2022. PMID: 36163279 Free PMC article.
Evolution of regulatory signatures in primate cortical neurons at cell-type resolution.
Kozlenkov A, Vermunt MW, Apontes P, Li J, Hao K, Sherwood CC, Hof PR, Ely JJ, Wegner M, Mukamel EA, Creyghton MP, Koonin EV, Dracheva S. Kozlenkov A, et al. Among authors: apontes p. Proc Natl Acad Sci U S A. 2020 Nov 10;117(45):28422-28432. doi: 10.1073/pnas.2011884117. Epub 2020 Oct 27. Proc Natl Acad Sci U S A. 2020. PMID: 33109720 Free PMC article.
DNA Methylation Profiling of Human Prefrontal Cortex Neurons in Heroin Users Shows Significant Difference between Genomic Contexts of Hyper- and Hypomethylation and a Younger Epigenetic Age.
Kozlenkov A, Jaffe AE, Timashpolsky A, Apontes P, Rudchenko S, Barbu M, Byne W, Hurd YL, Horvath S, Dracheva S. Kozlenkov A, et al. Among authors: apontes p. Genes (Basel). 2017 May 30;8(6):152. doi: 10.3390/genes8060152. Genes (Basel). 2017. PMID: 28556790 Free PMC article.
Molecular mechanism of inhibition of survivin transcription by the GC-rich sequence-selective DNA binding antitumor agent, hedamycin: evidence of survivin down-regulation associated with drug sensitivity.
Wu J, Ling X, Pan D, Apontes P, Song L, Liang P, Altieri DC, Beerman T, Li F. Wu J, et al. Among authors: apontes p. J Biol Chem. 2005 Mar 11;280(10):9745-51. doi: 10.1074/jbc.M409350200. Epub 2005 Jan 5. J Biol Chem. 2005. PMID: 15637054 Free PMC article.
17 results