Aplin AE - Search Results

1

Kinome profiling identifies MARK3 and STK10 as potential therapeutic targets in uveal melanoma.

Baqai U, Kurimchak AM, Trachtenberg IV, Purwin TJ, Haj JI, Han A, Luo K, Pachon NF, Jeon A, Chua V, Davies MA, Gutkind JS, Benovic JL, Duncan JS, Aplin AE. Baqai U, et al. Among authors: aplin ae. J Biol Chem. 2023 Dec;299(12):105418. doi: 10.1016/j.jbc.2023.105418. Epub 2023 Nov 3. J Biol Chem. 2023. PMID: 37923138 Free PMC article.

2

Adhesion-dependent activation of the ERK1/2 cascade is by-passed in melanoma cells.

Conner SR, Scott G, Aplin AE. Conner SR, et al. Among authors: aplin ae. J Biol Chem. 2003 Sep 5;278(36):34548-54. doi: 10.1074/jbc.M305797200. Epub 2003 Jun 23. J Biol Chem. 2003. PMID: 12821662 Free article.

3

Cyclin D3 expression in melanoma cells is regulated by adhesion-dependent phosphatidylinositol 3-kinase signaling and contributes to G1-S progression.

Spofford LS, Abel EV, Boisvert-Adamo K, Aplin AE. Spofford LS, et al. Among authors: aplin ae. J Biol Chem. 2006 Sep 1;281(35):25644-51. doi: 10.1074/jbc.M600197200. Epub 2006 Jun 29. J Biol Chem. 2006. PMID: 16815849 Free PMC article.

4

SHOC2 and CRAF mediate ERK1/2 reactivation in mutant NRAS-mediated resistance to RAF inhibitor.

Kaplan FM, Kugel CH 3rd, Dadpey N, Shao Y, Abel EV, Aplin AE. Kaplan FM, et al. Among authors: aplin ae. J Biol Chem. 2012 Dec 7;287(50):41797-807. doi: 10.1074/jbc.M112.390906. Epub 2012 Oct 17. J Biol Chem. 2012. PMID: 23076151 Free PMC article.

5

Function-blocking ERBB3 antibody inhibits the adaptive response to RAF inhibitor.

Kugel CH 3rd, Hartsough EJ, Davies MA, Setiady YY, Aplin AE. Kugel CH 3rd, et al. Among authors: aplin ae. Cancer Res. 2014 Aug 1;74(15):4122-32. doi: 10.1158/0008-5472.CAN-14-0464. Epub 2014 Jul 17. Cancer Res. 2014. PMID: 25035390 Free PMC article.

6

Sestrin2 protein positively regulates AKT enzyme signaling and survival in human squamous cell carcinoma and melanoma cells.

Zhao B, Shah P, Budanov AV, Qiang L, Ming M, Aplin A, Sims DM, He YY. Zhao B, et al. J Biol Chem. 2014 Dec 26;289(52):35806-14. doi: 10.1074/jbc.M114.595397. Epub 2014 Nov 6. J Biol Chem. 2014. PMID: 25378405 Free PMC article.

7

RAC1 P29S regulates PD-L1 expression in melanoma.

Vu HL, Rosenbaum S, Purwin TJ, Davies MA, Aplin AE. Vu HL, et al. Among authors: aplin ae. Pigment Cell Melanoma Res. 2015 Sep;28(5):590-8. doi: 10.1111/pcmr.12392. Pigment Cell Melanoma Res. 2015. PMID: 26176707 Free PMC article.

8

PAX3 and FOXD3 Promote CXCR4 Expression in Melanoma.

Kubic JD, Lui JW, Little EC, Ludvik AE, Konda S, Salgia R, Aplin AE, Lang D. Kubic JD, et al. Among authors: aplin ae. J Biol Chem. 2015 Sep 4;290(36):21901-14. doi: 10.1074/jbc.M115.670976. Epub 2015 Jul 23. J Biol Chem. 2015. PMID: 26205821 Free PMC article.

9

ErbB3-ErbB2 Complexes as a Therapeutic Target in a Subset of Wild-type BRAF/NRAS Cutaneous Melanomas.

Capparelli C, Rosenbaum S, Berman-Booty LD, Salhi A, Gaborit N, Zhan T, Chervoneva I, Roszik J, Woodman SE, Davies MA, Setiady YY, Osman I, Yarden Y, Aplin AE. Capparelli C, et al. Among authors: aplin ae. Cancer Res. 2015 Sep 1;75(17):3554-67. doi: 10.1158/0008-5472.CAN-14-2959. Epub 2015 Jul 23. Cancer Res. 2015. PMID: 26206558 Free PMC article.

10

Fibroblast-derived neuregulin 1 promotes compensatory ErbB3 receptor signaling in mutant BRAF melanoma.

Capparelli C, Rosenbaum S, Berger AC, Aplin AE. Capparelli C, et al. Among authors: aplin ae. J Biol Chem. 2015 Oct 2;290(40):24267-77. doi: 10.1074/jbc.M115.657270. Epub 2015 Aug 12. J Biol Chem. 2015. PMID: 26269601 Free PMC article.

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