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The landscape of cancer cell line metabolism.
Nat Med. 2019 May;25(5):850-860. doi: 10.1038/s41591-019-0404-8. Epub 2019 May 8.
Nat Med. 2019.
PMID: 31068703
Free PMC article.
PAX8 activates metabolic genes via enhancer elements in Renal Cell Carcinoma.
Bleu M, Gaulis S, Lopes R, Sprouffske K, Apfel V, Holwerda S, Pregnolato M, Yildiz U, Cordoʹ V, Dost AFM, Knehr J, Carbone W, Lohmann F, Lin CY, Bradner JE, Kauffmann A, Tordella L, Roma G, Galli GG.
Bleu M, et al. Among authors: apfel v.
Nat Commun. 2019 Aug 20;10(1):3739. doi: 10.1038/s41467-019-11672-1.
Nat Commun. 2019.
PMID: 31431624
Free PMC article.
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PAX8 and MECOM are interaction partners driving ovarian cancer.
Bleu M, Mermet-Meillon F, Apfel V, Barys L, Holzer L, Bachmann Salvy M, Lopes R, Amorim Monteiro Barbosa I, Delmas C, Hinniger A, Chau S, Kaufmann M, Haenni S, Berneiser K, Wahle M, Moravec I, Vissières A, Poetsch T, Ahrné E, Carte N, Voshol J, Bechter E, Hamon J, Meyerhofer M, Erdmann D, Fischer M, Stachyra T, Freuler F, Gutmann S, Fernández C, Schmelzle T, Naumann U, Roma G, Lawrenson K, Nieto-Oberhuber C, Cobos-Correa A, Ferretti S, Schübeler D, Galli GG.
Bleu M, et al. Among authors: apfel v.
Nat Commun. 2021 Apr 26;12(1):2442. doi: 10.1038/s41467-021-22708-w.
Nat Commun. 2021.
PMID: 33903593
Free PMC article.
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Therapeutic Assessment of Targeting ASNS Combined with l-Asparaginase Treatment in Solid Tumors and Investigation of Resistance Mechanisms.
Apfel V, Begue D, Cordo' V, Holzer L, Martinuzzi L, Buhles A, Kerr G, Barbosa I, Naumann U, Piquet M, Ruddy D, Weiss A, Ferretti S, Almeida R, Bonenfant D, Tordella L, Galli GG.
Apfel V, et al.
ACS Pharmacol Transl Sci. 2021 Jan 13;4(1):327-337. doi: 10.1021/acsptsci.0c00196. eCollection 2021 Feb 12.
ACS Pharmacol Transl Sci. 2021.
PMID: 33615182
Free PMC article.
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Systematic dissection of transcriptional regulatory networks by genome-scale and single-cell CRISPR screens.
Lopes R, Sprouffske K, Sheng C, Uijttewaal ECH, Wesdorp AE, Dahinden J, Wengert S, Diaz-Miyar J, Yildiz U, Bleu M, Apfel V, Mermet-Meillon F, Krese R, Eder M, Olsen AV, Hoppe P, Knehr J, Carbone W, Cuttat R, Waldt A, Altorfer M, Naumann U, Weischenfeldt J, deWeck A, Kauffmann A, Roma G, Schübeler D, Galli GG.
Lopes R, et al. Among authors: apfel v.
Sci Adv. 2021 Jul 2;7(27):eabf5733. doi: 10.1126/sciadv.abf5733. Print 2021 Jul.
Sci Adv. 2021.
PMID: 34215580
Free PMC article.
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GPR91 senses extracellular succinate released from inflammatory macrophages and exacerbates rheumatoid arthritis.
Littlewood-Evans A, Sarret S, Apfel V, Loesle P, Dawson J, Zhang J, Muller A, Tigani B, Kneuer R, Patel S, Valeaux S, Gommermann N, Rubic-Schneider T, Junt T, Carballido JM.
Littlewood-Evans A, et al. Among authors: apfel v.
J Exp Med. 2016 Aug 22;213(9):1655-62. doi: 10.1084/jem.20160061. Epub 2016 Aug 1.
J Exp Med. 2016.
PMID: 27481132
Free PMC article.
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Treatment for vaginal agenesis: A prospective and comparative study between vaginal dilation and surgical neovaginoplasty.
Apfel VR, Takano CC, Marquini GV, de Jarmy di Bella ZIK, Girão MJBC, Sartori MGF.
Apfel VR, et al.
Int J Gynaecol Obstet. 2022 Jun;157(3):574-581. doi: 10.1002/ijgo.13931. Epub 2021 Oct 4.
Int J Gynaecol Obstet. 2022.
PMID: 34534375
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An interesting finding in the uterine cervix: Schistosoma hematobium calcified eggs.
Toller A, Scopin AC, Apfel V, Prigenzi KC, Tso FK, Focchi GR, Speck N, Ribalta J.
Toller A, et al. Among authors: apfel v.
Autops Case Rep. 2015 Jun 30;5(2):41-4. doi: 10.4322/acr.2015.003. eCollection 2015 Apr-Jun.
Autops Case Rep. 2015.
PMID: 26484333
Free PMC article.
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