Anzai Y - Search Results

1

Computational-Based Mechanistic Study and Engineering of Cytochrome P450 MycG for Selective Oxidation of 16-Membered Macrolide Antibiotics.

Yang S, DeMars MD 2nd, Grandner JM, Olson NM, Anzai Y, Sherman DH, Houk KN. Yang S, et al. Among authors: anzai y. J Am Chem Soc. 2020 Oct 21;142(42):17981-17988. doi: 10.1021/jacs.0c04388. Epub 2020 Oct 8. J Am Chem Soc. 2020. PMID: 33030347 Free PMC article.

2

Functional analysis of MycCI and MycG, cytochrome P450 enzymes involved in biosynthesis of mycinamicin macrolide antibiotics.

Anzai Y, Li S, Chaulagain MR, Kinoshita K, Kato F, Montgomery J, Sherman DH. Anzai Y, et al. Chem Biol. 2008 Sep 22;15(9):950-9. doi: 10.1016/j.chembiol.2008.07.014. Chem Biol. 2008. PMID: 18804032 Free PMC article.

3

Functional analysis of MycE and MycF, two O-methyltransferases involved in the biosynthesis of mycinamicin macrolide antibiotics.

Li S, Anzai Y, Kinoshita K, Kato F, Sherman DH. Li S, et al. Among authors: anzai y. Chembiochem. 2009 May 25;10(8):1297-301. doi: 10.1002/cbic.200900088. Chembiochem. 2009. PMID: 19415708 Free PMC article.

4

Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.

Carlson JC, Fortman JL, Anzai Y, Li S, Burr DA, Sherman DH. Carlson JC, et al. Among authors: anzai y. Chembiochem. 2010 Mar 1;11(4):564-72. doi: 10.1002/cbic.200900658. Chembiochem. 2010. PMID: 20127927 Free PMC article.

5

Gene targeting for O-methyltransferase genes, mycE and mycF, on the chromosome of Micromonospora griseorubida producing mycinamicin with a disruption cassette containing the bacteriophage phi C31 attB attachment site.

Tsukada S, Anzai Y, Li S, Kinoshita K, Sherman DH, Kato F. Tsukada S, et al. Among authors: anzai y. FEMS Microbiol Lett. 2010 Mar;304(2):148-56. doi: 10.1111/j.1574-6968.2010.01899.x. Epub 2010 Jan 11. FEMS Microbiol Lett. 2010. PMID: 20158522 Free article.

6

Tirandamycin biosynthesis is mediated by co-dependent oxidative enzymes.

Carlson JC, Li S, Gunatilleke SS, Anzai Y, Burr DA, Podust LM, Sherman DH. Carlson JC, et al. Among authors: anzai y. Nat Chem. 2011 Jul 17;3(8):628-33. doi: 10.1038/nchem.1087. Nat Chem. 2011. PMID: 21778983 Free PMC article.

7

A new structural form in the SAM/metal-dependent o‑methyltransferase family: MycE from the mycinamicin biosynthetic pathway.

Akey DL, Li S, Konwerski JR, Confer LA, Bernard SM, Anzai Y, Kato F, Sherman DH, Smith JL. Akey DL, et al. Among authors: anzai y. J Mol Biol. 2011 Oct 21;413(2):438-50. doi: 10.1016/j.jmb.2011.08.040. Epub 2011 Aug 23. J Mol Biol. 2011. PMID: 21884704 Free PMC article.

8

Function of cytochrome P450 enzymes MycCI and MycG in Micromonospora griseorubida, a producer of the macrolide antibiotic mycinamicin.

Anzai Y, Tsukada S, Sakai A, Masuda R, Harada C, Domeki A, Li S, Kinoshita K, Sherman DH, Kato F. Anzai Y, et al. Antimicrob Agents Chemother. 2012 Jul;56(7):3648-56. doi: 10.1128/AAC.06063-11. Epub 2012 Apr 30. Antimicrob Agents Chemother. 2012. PMID: 22547618 Free PMC article.

9

Production of a hybrid 16-membered macrolide antibiotic by genetic engineering of Micromonospora sp. TPMA0041.

Sakai A, Mitsumori A, Furukawa M, Kinoshita K, Anzai Y, Kato F. Sakai A, et al. Among authors: anzai y. J Ind Microbiol Biotechnol. 2012 Nov;39(11):1693-701. doi: 10.1007/s10295-012-1173-2. Epub 2012 Jul 29. J Ind Microbiol Biotechnol. 2012. PMID: 22842988

10

Substrate recognition by the multifunctional cytochrome P450 MycG in mycinamicin hydroxylation and epoxidation reactions.

Li S, Tietz DR, Rutaganira FU, Kells PM, Anzai Y, Kato F, Pochapsky TC, Sherman DH, Podust LM. Li S, et al. Among authors: anzai y. J Biol Chem. 2012 Nov 2;287(45):37880-90. doi: 10.1074/jbc.M112.410340. Epub 2012 Sep 5. J Biol Chem. 2012. PMID: 22952225 Free PMC article.

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