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Page 1
Immunogenicity of MultiTEP-Platform-Based Recombinant Protein Vaccine, PV-1950R, Targeting Three B-Cell Antigenic Determinants of Pathological α-Synuclein.
Zagorski K, Chailyan G, Hovakimyan A, Antonyan T, Kiani Shabestari S, Petrushina I, Davtyan H, Cribbs DH, Blurton-Jones M, Masliah E, Agadjanyan MG, Ghochikyan A. Zagorski K, et al. Among authors: antonyan t. Int J Mol Sci. 2022 May 29;23(11):6080. doi: 10.3390/ijms23116080. Int J Mol Sci. 2022. PMID: 35682759 Free PMC article.
A MultiTEP platform-based epitope vaccine targeting the phosphatase activating domain (PAD) of tau: therapeutic efficacy in PS19 mice.
Hovakimyan A, Antonyan T, Shabestari SK, Svystun O, Chailyan G, Coburn MA, Carlen-Jones W, Petrushina I, Chadarevian JP, Zagorski K, Petrovsky N, Cribbs DH, Agadjanyan MG, Ghochikyan A, Davtyan H. Hovakimyan A, et al. Among authors: antonyan t. Sci Rep. 2019 Oct 29;9(1):15455. doi: 10.1038/s41598-019-51809-2. Sci Rep. 2019. PMID: 31664089 Free PMC article.
Testing a MultiTEP-based combination vaccine to reduce Aβ and tau pathology in Tau22/5xFAD bigenic mice.
Davtyan H, Hovakimyan A, Kiani Shabestari S, Antonyan T, Coburn MA, Zagorski K, Chailyan G, Petrushina I, Svystun O, Danhash E, Petrovsky N, Cribbs DH, Agadjanyan MG, Blurton-Jones M, Ghochikyan A. Davtyan H, et al. Among authors: antonyan t. Alzheimers Res Ther. 2019 Dec 17;11(1):107. doi: 10.1186/s13195-019-0556-2. Alzheimers Res Ther. 2019. PMID: 31847886 Free PMC article.
Efficacy and immunogenicity of MultiTEP-based DNA vaccines targeting human α-synuclein: prelude for IND enabling studies.
Kim C, Hovakimyan A, Zagorski K, Antonyan T, Petrushina I, Davtyan H, Chailyan G, Hasselmann J, Iba M, Adame A, Rockenstein E, Szabo M, Blurton-Jones M, Cribbs DH, Ghochikyan A, Masliah E, Agadjanyan MG. Kim C, et al. Among authors: antonyan t. NPJ Vaccines. 2022 Jan 10;7(1):1. doi: 10.1038/s41541-021-00424-2. NPJ Vaccines. 2022. PMID: 35013319 Free PMC article.
Immunogenicity of MultiTEP platform technology-based Tau vaccine in non-human primates.
Hovakimyan A, Zagorski K, Chailyan G, Antonyan T, Melikyan L, Petrushina I, Batt DG, King O, Ghazaryan M, Donthi A, Foose C, Petrovsky N, Cribbs DH, Agadjanyan MG, Ghochikyan A. Hovakimyan A, et al. Among authors: antonyan t. NPJ Vaccines. 2022 Oct 12;7(1):117. doi: 10.1038/s41541-022-00544-3. NPJ Vaccines. 2022. PMID: 36224191 Free PMC article.
Characterization and preclinical evaluation of the cGMP grade DNA based vaccine, AV-1959D to enter the first-in-human clinical trials.
Petrushina I, Hovakimyan A, Harahap-Carrillo IS, Davtyan H, Antonyan T, Chailyan G, Kazarian K, Antonenko M, Jullienne A, Hamer MM, Obenaus A, King O, Zagorski K, Blurton-Jones M, Cribbs DH, Lander H, Ghochikyan A, Agadjanyan MG. Petrushina I, et al. Among authors: antonyan t. Neurobiol Dis. 2020 Jun;139:104823. doi: 10.1016/j.nbd.2020.104823. Epub 2020 Feb 28. Neurobiol Dis. 2020. PMID: 32119976 Free PMC article. Review.
Active immunization with tau epitope in a mouse model of tauopathy induced strong antibody response together with improvement in short memory and pSer396-tau pathology.
Joly-Amado A, Davtyan H, Serraneau K, Jules P, Zitnyar A, Pressman E, Zagorski K, Antonyan T, Hovakimyan A, Paek HJ, Gordon MN, Cribbs DH, Petrovsky N, Agadjanyan MG, Ghochikyan A, Morgan D. Joly-Amado A, et al. Among authors: antonyan t. Neurobiol Dis. 2020 Feb;134:104636. doi: 10.1016/j.nbd.2019.104636. Epub 2019 Oct 17. Neurobiol Dis. 2020. PMID: 31629891 Free PMC article.
Author Correction: Efficacy and immunogenicity of MultiTEP-based DNA vaccines targeting human α-synuclein: prelude for IND enabling studies.
Kim C, Hovakimyan A, Zagorski K, Antonyan T, Petrushina I, Davtyan H, Chailyan G, Hasselmann J, Iba M, Adame A, Rockenstein E, Szabo M, Blurton-Jones M, Cribbs DH, Ghochikyan A, Masliah E, Agadjanyan MG. Kim C, et al. Among authors: antonyan t. NPJ Vaccines. 2023 Jul 17;8(1):105. doi: 10.1038/s41541-023-00703-0. NPJ Vaccines. 2023. PMID: 37460684 Free PMC article. No abstract available.