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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2003 2
2005 1
2007 2
2008 4
2009 2
2010 1
2011 4
2012 3
2013 3
2014 4
2015 3
2016 9
2017 6
2018 3
2019 5
2020 9
2021 6
2022 6
2023 5
2024 1

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69 results

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Page 1
AMALPHI: A Machine Learning Platform for Predicting Drug-Induced PhospholIpidosis.
Lomuscio MC, Abate C, Alberga D, Laghezza A, Corriero N, Colabufo NA, Saviano M, Delre P, Mangiatordi GF. Lomuscio MC, et al. Among authors: laghezza a. Mol Pharm. 2024 Feb 5;21(2):864-872. doi: 10.1021/acs.molpharmaceut.3c00964. Epub 2023 Dec 22. Mol Pharm. 2024. PMID: 38134445 Free PMC article.
A New Antidiabetic Agent Showing Short- and Long-Term Effects Due to Peroxisome Proliferator-Activated Receptor Alpha/Gamma Dual Agonism and Mitochondrial Pyruvate Carrier Inhibition.
Laghezza A, Cerchia C, Genovese M, Leuci R, Pranzini E, Santi A, Brunetti L, Piemontese L, Tortorella P, Biswas A, Singh RP, Tambe S, Ca S, Pattnaik AK, Jayaprakash V, Paoli P, Lavecchia A, Loiodice F. Laghezza A, et al. J Med Chem. 2023 Mar 9;66(5):3566-3587. doi: 10.1021/acs.jmedchem.2c02093. Epub 2023 Feb 15. J Med Chem. 2023. PMID: 36790935
Development of N-(1-Adamantyl)benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty Acid Amide Hydrolase.
Intranuovo F, Brunetti L, DelRe P, Mangiatordi GF, Stefanachi A, Laghezza A, Niso M, Leonetti F, Loiodice F, Ligresti A, Kostrzewa M, Brea J, Loza MI, Sotelo E, Saviano M, Colabufo NA, Riganti C, Abate C, Contino M. Intranuovo F, et al. Among authors: laghezza a. J Med Chem. 2023 Jan 12;66(1):235-250. doi: 10.1021/acs.jmedchem.2c01084. Epub 2022 Dec 21. J Med Chem. 2023. PMID: 36542836
Novel Phenothiazine/Donepezil-like Hybrids Endowed with Antioxidant Activity for a Multi-Target Approach to the Therapy of Alzheimer's Disease.
Carocci A, Barbarossa A, Leuci R, Carrieri A, Brunetti L, Laghezza A, Catto M, Limongelli F, Chaves S, Tortorella P, Altomare CD, Santos MA, Loiodice F, Piemontese L. Carocci A, et al. Among authors: laghezza a. Antioxidants (Basel). 2022 Aug 23;11(9):1631. doi: 10.3390/antiox11091631. Antioxidants (Basel). 2022. PMID: 36139705 Free PMC article.
Structure-based design of novel donepezil-like hybrids for a multi-target approach to the therapy of Alzheimer's disease.
Brunetti L, Leuci R, Carrieri A, Catto M, Occhineri S, Vinci G, Gambacorta L, Baltrukevich H, Chaves S, Laghezza A, Altomare CD, Tortorella P, Santos MA, Loiodice F, Piemontese L. Brunetti L, et al. Among authors: laghezza a. Eur J Med Chem. 2022 Jul 5;237:114358. doi: 10.1016/j.ejmech.2022.114358. Epub 2022 Apr 14. Eur J Med Chem. 2022. PMID: 35462163
A chemoinformatics search for peroxisome proliferator-activated receptors ligands revealed a new pan-agonist able to reduce lipid accumulation and improve insulin sensitivity.
Sblano S, Cerchia C, Laghezza A, Piemontese L, Brunetti L, Leuci R, Gilardi F, Thomas A, Genovese M, Santi A, Tortorella P, Paoli P, Lavecchia A, Loiodice F. Sblano S, et al. Among authors: laghezza a. Eur J Med Chem. 2022 May 5;235:114240. doi: 10.1016/j.ejmech.2022.114240. Epub 2022 Mar 16. Eur J Med Chem. 2022. PMID: 35325635
A New Series of Aryloxyacetic Acids Endowed with Multi-Target Activity towards Peroxisome Proliferator-Activated Receptors (PPARs), Fatty Acid Amide Hydrolase (FAAH), and Acetylcholinesterase (AChE).
Leuci R, Brunetti L, Laghezza A, Piemontese L, Carrieri A, Pisani L, Tortorella P, Catto M, Loiodice F. Leuci R, et al. Among authors: laghezza a. Molecules. 2022 Jan 31;27(3):958. doi: 10.3390/molecules27030958. Molecules. 2022. PMID: 35164223 Free PMC article.
69 results