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Metalloproteinase inhibition reduces AML growth, prevents stem cell loss, and improves chemotherapy effectiveness.
Pirillo C, Birch F, Tissot FS, Anton SG, Haltalli M, Tini V, Kong I, Piot C, Partridge B, Pospori C, Keeshan K, Santamaria S, Hawkins E, Falini B, Marra A, Duarte D, Lee CF, Roberts E, Lo Celso C. Pirillo C, et al. Among authors: anton sg. Blood Adv. 2022 May 24;6(10):3126-3141. doi: 10.1182/bloodadvances.2021004321. Blood Adv. 2022. PMID: 35157757 Free PMC article.
Manipulating niche composition limits damage to haematopoietic stem cells during Plasmodium infection.
Haltalli MLR, Watcham S, Wilson NK, Eilers K, Lipien A, Ang H, Birch F, Anton SG, Pirillo C, Ruivo N, Vainieri ML, Pospori C, Sinden RE, Luis TC, Langhorne J, Duffy KR, Göttgens B, Blagborough AM, Lo Celso C. Haltalli MLR, et al. Among authors: anton sg. Nat Cell Biol. 2020 Dec;22(12):1399-1410. doi: 10.1038/s41556-020-00601-w. Epub 2020 Nov 23. Nat Cell Biol. 2020. PMID: 33230302 Free PMC article.