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Acarbose presents in vitro and in vivo antileishmanial activity against Leishmania infantum and is a promising therapeutic candidate against visceral leishmaniasis.
Costa RR, Oliveira-da-Silva JA, Reis TAR, Tavares GSV, Mendonça DVC, Freitas CS, Lage DP, Martins VT, Antinarelli LMR, Machado AS, Bandeira RS, Ludolf F, Santos TTO, Brito RCF, Humbert MV, Menezes-Souza D, Duarte MC, Chávez-Fumagalli MA, Roatt BM, Coimbra ES, Coelho EAF. Costa RR, et al. Among authors: antinarelli lmr. Med Microbiol Immunol. 2021 Jun;210(2-3):133-147. doi: 10.1007/s00430-021-00707-4. Epub 2021 Apr 18. Med Microbiol Immunol. 2021. PMID: 33870453 Free PMC article.
4-Aminoquinoline Derivatives as Potential Antileishmanial Agents.
Antinarelli LM, Dias RM, Souza IO, Lima WP, Gameiro J, da Silva AD, Coimbra ES. Antinarelli LM, et al. Chem Biol Drug Des. 2015 Oct;86(4):704-14. doi: 10.1111/cbdd.12540. Epub 2015 Mar 11. Chem Biol Drug Des. 2015. PMID: 25682728
A Pluronic® F127-based polymeric micelle system containing an antileishmanial molecule is immunotherapeutic and effective in the treatment against Leishmania amazonensis infection.
Tavares GSV, Mendonça DVC, Miyazaki CK, Lage DP, Soyer TG, Carvalho LM, Ottoni FM, Dias DS, Ribeiro PAF, Antinarelli LMR, Ludolf F, Duarte MC, Coimbra ES, Chávez-Fumagalli MA, Roatt BM, Menezes-Souza D, Barichello JM, Alves RJ, Coelho EAF. Tavares GSV, et al. Among authors: antinarelli lmr. Parasitol Int. 2019 Feb;68(1):63-72. doi: 10.1016/j.parint.2018.10.005. Epub 2018 Oct 16. Parasitol Int. 2019. PMID: 30339837
33 results