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Mapping the genomic landscape of multidrug resistance in Plasmodium falciparum and its impact on parasite fitness.
Mok S, Yeo T, Hong D, Shears MJ, Ross LS, Ward KE, Dhingra SK, Kanai M, Bridgford JL, Tripathi AK, Mlambo G, Burkhard AY, Ansbro MR, Fairhurst KJ, Gil-Iturbe E, Park H, Rozenberg FD, Kim J, Mancia F, Fairhurst RM, Quick M, Uhlemann AC, Sinnis P, Fidock DA. Mok S, et al. Among authors: ansbro mr. Sci Adv. 2023 Nov 10;9(45):eadi2364. doi: 10.1126/sciadv.adi2364. Epub 2023 Nov 8. Sci Adv. 2023. PMID: 37939186 Free PMC article.
Overexpression of plasmepsin II and plasmepsin III does not directly cause reduction in Plasmodium falciparum sensitivity to artesunate, chloroquine and piperaquine.
Loesbanluechai D, Kotanan N, de Cozar C, Kochakarn T, Ansbro MR, Chotivanich K, White NJ, Wilairat P, Lee MCS, Gamo FJ, Sanz LM, Chookajorn T, Kümpornsin K. Loesbanluechai D, et al. Among authors: ansbro mr. Int J Parasitol Drugs Drug Resist. 2019 Apr;9:16-22. doi: 10.1016/j.ijpddr.2018.11.004. Epub 2018 Dec 1. Int J Parasitol Drugs Drug Resist. 2019. PMID: 30580023 Free PMC article.
Modulation of Triple Artemisinin-Based Combination Therapy Pharmacodynamics by Plasmodium falciparum Genotype.
Ansbro MR, Itkin Z, Chen L, Zahoranszky-Kohalmi G, Amaratunga C, Miotto O, Peryea T, Hobbs CV, Suon S, Sá JM, Dondorp AM, van der Pluijm RW, Wellems TE, Simeonov A, Eastman RT. Ansbro MR, et al. ACS Pharmacol Transl Sci. 2020 Nov 2;3(6):1144-1157. doi: 10.1021/acsptsci.0c00110. eCollection 2020 Dec 11. ACS Pharmacol Transl Sci. 2020. PMID: 33344893 Free PMC article.
Distinct transcriptional profiles of maternal and fetal placental macrophages at term are associated with gravidity.
Ozarslan N, Robinson JF, Buarpung S, Kim MY, Ansbro MR, Akram J, Montoya DJ, Kamya MR, Kakuru A, Dorsey G, Rosenthal PJ, Cheng G, Feeney ME, Fisher SJ, Gaw SL. Ozarslan N, et al. Among authors: ansbro mr. bioRxiv [Preprint]. 2023 Sep 28:2023.09.25.559419. doi: 10.1101/2023.09.25.559419. bioRxiv. 2023. PMID: 37808856 Free PMC article. Preprint.
Drug-dependent inhibition of nucleotide hydrolysis in the heterodimeric ABC multidrug transporter PatAB from Streptococcus pneumoniae.
Guffick C, Hsieh PY, Ali A, Shi W, Howard J, Chinthapalli DK, Kong AC, Salaa I, Crouch LI, Ansbro MR, Isaacson SC, Singh H, Barrera NP, Nair AV, Robinson CV, Deery MJ, van Veen HW. Guffick C, et al. Among authors: ansbro mr. FEBS J. 2022 Jul;289(13):3770-3788. doi: 10.1111/febs.16366. Epub 2022 Feb 11. FEBS J. 2022. PMID: 35066976 Free PMC article.
Histone H3 K79 methylation states play distinct roles in UV-induced sister chromatid exchange and cell cycle checkpoint arrest in Saccharomyces cerevisiae.
Rossodivita AA, Boudoures AL, Mecoli JP, Steenkiste EM, Karl AL, Vines EM, Cole AM, Ansbro MR, Thompson JS. Rossodivita AA, et al. Among authors: ansbro mr. Nucleic Acids Res. 2014 Jun;42(10):6286-99. doi: 10.1093/nar/gku242. Epub 2014 Apr 19. Nucleic Acids Res. 2014. PMID: 24748660 Free PMC article.