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FDA Public Workshop Summary-Coccidioidomycosis (Valley Fever): Considerations for Development of Antifungal Drugs.
O'Shaughnessy E, Yasinskaya Y, Dixon C, Higgins K, Moore J, Reynolds K, Ampel NM, Angulo D, Blair JE, Catanzaro A, Galgiani JN, Garvey E, Johnson R, Larwood DJ, Lewis G, Purdie R, Rex JH, Shubitz LF, Stevens DA, Page SJ, Shukla SJ, Farley JJ, Nambiar S. O'Shaughnessy E, et al. Among authors: angulo d. Clin Infect Dis. 2022 Jun 10;74(11):2061-2066. doi: 10.1093/cid/ciab904. Clin Infect Dis. 2022. PMID: 34651656
Ibrexafungerp Versus Placebo for Vulvovaginal Candidiasis Treatment: A Phase 3, Randomized, Controlled Superiority Trial (VANISH 303).
Schwebke JR, Sobel R, Gersten JK, Sussman SA, Lederman SN, Jacobs MA, Chappell BT, Weinstein DL, Moffett AH, Azie NE, Angulo DA, Harriott IA, Borroto-Esoda K, Ghannoum MA, Nyirjesy P, Sobel JD. Schwebke JR, et al. Among authors: angulo da. Clin Infect Dis. 2022 Jun 10;74(11):1979-1985. doi: 10.1093/cid/ciab750. Clin Infect Dis. 2022. PMID: 34467969 Free PMC article. Clinical Trial.
Food and Drug Administration Public Workshop Summary-Development Considerations of Antifungal Drugs to Address Unmet Medical Need.
Yasinskaya Y, Bala S, Waack U, Dixon C, Higgins K, Moore JN, Jjingo CJ, O'Shaughnessy E, Colangelo P, Botgros R, Nambiar S, Angulo D, Dane A, Chiller T, Hodges MR, Sandison T, Hope W, Walsh TJ, Pappas P, Katragkou A, Kovanda L, Rex JH, Marr KA, Ostrosky-Zeichner L, Sekine S, Deshpande M, Shukla SJ, Farley J. Yasinskaya Y, et al. Among authors: angulo d. Clin Infect Dis. 2023 Aug 14;77(3):380-387. doi: 10.1093/cid/ciad195. Clin Infect Dis. 2023. PMID: 37021650
Preclinical Pharmacokinetics and Pharmacodynamic Target of SCY-078, a First-in-Class Orally Active Antifungal Glucan Synthesis Inhibitor, in Murine Models of Disseminated Candidiasis.
Wring SA, Randolph R, Park S, Abruzzo G, Chen Q, Flattery A, Garrett G, Peel M, Outcalt R, Powell K, Trucksis M, Angulo D, Borroto-Esoda K. Wring SA, et al. Among authors: angulo d. Antimicrob Agents Chemother. 2017 Mar 24;61(4):e02068-16. doi: 10.1128/AAC.02068-16. Print 2017 Apr. Antimicrob Agents Chemother. 2017. PMID: 28137806 Free PMC article.
SCY-078, a Novel Fungicidal Agent, Demonstrates Distribution to Tissues Associated with Fungal Infections during Mass Balance Studies with Intravenous and Oral [14C]SCY-078 in Albino and Pigmented Rats.
Wring S, Borroto-Esoda K, Solon E, Angulo D. Wring S, et al. Among authors: angulo d. Antimicrob Agents Chemother. 2019 Jan 29;63(2):e02119-18. doi: 10.1128/AAC.02119-18. Print 2019 Feb. Antimicrob Agents Chemother. 2019. PMID: 30478166 Free PMC article.
SCY-078 Is Fungicidal against Candida Species in Time-Kill Studies.
Scorneaux B, Angulo D, Borroto-Esoda K, Ghannoum M, Peel M, Wring S. Scorneaux B, et al. Among authors: angulo d. Antimicrob Agents Chemother. 2017 Feb 23;61(3):e01961-16. doi: 10.1128/AAC.01961-16. Print 2017 Mar. Antimicrob Agents Chemother. 2017. PMID: 28069658 Free PMC article.
64 results