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Bariatric-metabolic surgery versus lifestyle intervention plus best medical care in non-alcoholic steatohepatitis (BRAVES): a multicentre, open-label, randomised trial.
Verrastro O, Panunzi S, Castagneto-Gissey L, De Gaetano A, Lembo E, Capristo E, Guidone C, Angelini G, Pennestrì F, Sessa L, Vecchio FM, Riccardi L, Zocco MA, Boskoski I, Casella-Mariolo JR, Marini P, Pompili M, Casella G, Fiori E, Rubino F, Bornstein SR, Raffaelli M, Mingrone G. Verrastro O, et al. Among authors: angelini g. Lancet. 2023 May 27;401(10390):1786-1797. doi: 10.1016/S0140-6736(23)00634-7. Epub 2023 Apr 21. Lancet. 2023. PMID: 37088093 Free article. Clinical Trial.
Insulin Resistance, Microbiota, and Fat Distribution Changes by a New Model of Vertical Sleeve Gastrectomy in Obese Rats.
Basso N, Soricelli E, Castagneto-Gissey L, Casella G, Albanese D, Fava F, Donati C, Tuohy K, Angelini G, La Neve F, Severino A, Kamvissi-Lorenz V, Birkenfeld AL, Bornstein S, Manco M, Mingrone G. Basso N, et al. Among authors: angelini g. Diabetes. 2016 Oct;65(10):2990-3001. doi: 10.2337/db16-0039. Epub 2016 Jul 18. Diabetes. 2016. PMID: 27431457
Simulation of gastric bypass effects on glucose metabolism and non-alcoholic fatty liver disease with the Sleeveballoon device.
Casella-Mariolo J, Castagneto-Gissey L, Angelini G, Zoli A, Marini P, Bornstein SR, Pournaras DJ, Rubino F, le Roux CW, Mingrone G, Casella G. Casella-Mariolo J, et al. Among authors: angelini g. EBioMedicine. 2019 Aug;46:452-462. doi: 10.1016/j.ebiom.2019.07.069. Epub 2019 Aug 7. EBioMedicine. 2019. PMID: 31401193 Free PMC article.
The jejunum is the key factor in insulin resistance.
Castagneto-Gissey L, Angelini G, Casella-Mariolo JR, Marini P, Mingrone G, Casella G. Castagneto-Gissey L, et al. Among authors: angelini g. Surg Obes Relat Dis. 2020 Apr;16(4):509-519. doi: 10.1016/j.soard.2019.12.024. Epub 2020 Jan 3. Surg Obes Relat Dis. 2020. PMID: 32008978
Duodenal-jejunal bypass improves nonalcoholic fatty liver disease independently of weight loss in rodents with diet-induced obesity.
Angelini G, Castagneto-Gissey L, Casella-Mariolo J, Caristo ME, Russo MF, Lembo E, Verrastro O, Stefanizzi G, Marini PL, Casella G, Bornstein SR, Rubino F, Mingrone G. Angelini G, et al. Am J Physiol Gastrointest Liver Physiol. 2020 Oct 1;319(4):G502-G511. doi: 10.1152/ajpgi.00357.2019. Epub 2020 Aug 19. Am J Physiol Gastrointest Liver Physiol. 2020. PMID: 32812775 Free article.
Small intestinal metabolism is central to whole-body insulin resistance.
Angelini G, Salinari S, Castagneto-Gissey L, Bertuzzi A, Casella-Mariolo J, Ahlin S, Boskoski I, Gaggini M, Raffaelli M, Costamagna G, Casella G, Marini PL, Gastaldelli A, Bornstein S, Mingrone G. Angelini G, et al. Gut. 2021 Jun;70(6):1098-1109. doi: 10.1136/gutjnl-2020-322073. Epub 2020 Sep 29. Gut. 2021. PMID: 32994312
1,190 results