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Year Number of Results
2016 2
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2019 3
2020 4
2021 2
2022 3
2023 4
2024 1

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Page 1
Development of a GC-376 Based Peptidomimetic PROTAC as a Degrader of 3-Chymotrypsin-like Protease of SARS-CoV-2.
Grifagni D, Lenci E, De Santis A, Orsetti A, Barracchia CG, Tedesco F, Bellini Puglielli R, Lucarelli F, Lauriola A, Assfalg M, Cantini F, Calderone V, Guardavaccaro D, Trabocchi A, D'Onofrio M, Ciofi-Baffoni S. Grifagni D, et al. Among authors: lauriola a. ACS Med Chem Lett. 2024 Jan 10;15(2):250-257. doi: 10.1021/acsmedchemlett.3c00498. eCollection 2024 Feb 8. ACS Med Chem Lett. 2024. PMID: 38352832
SCFβTrCP-mediated degradation of SHARP1 in triple-negative breast cancer.
Enriqué Steinberg JH, Rossi FA, Magliozzi R, Yuniati L, Santucci M, Rossi M, Guardavaccaro D, Lauriola A. Enriqué Steinberg JH, et al. Among authors: lauriola a. Cell Death Dis. 2023 Nov 8;14(11):726. doi: 10.1038/s41419-023-06253-6. Cell Death Dis. 2023. PMID: 37938564 Free PMC article.
Expression of FBXW11 in normal and disease-associated osteogenic cells.
Dalle Carbonare L, Gomez Lira M, Minoia A, Bertacco J, Orsi S, Lauriola A, Li Vigni V, Gandini A, Antoniazzi F, Zipeto D, Mottes M, Bhandary L, Guardavaccaro D, Valenti MT. Dalle Carbonare L, et al. Among authors: lauriola a. J Cell Mol Med. 2023 Jun;27(11):1580-1591. doi: 10.1111/jcmm.17767. Epub 2023 May 17. J Cell Mol Med. 2023. PMID: 37199076 Free PMC article.
Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth.
Costantino L, Ferrari S, Santucci M, Salo-Ahen OMH, Carosati E, Franchini S, Lauriola A, Pozzi C, Trande M, Gozzi G, Saxena P, Cannazza G, Losi L, Cardinale D, Venturelli A, Quotadamo A, Linciano P, Tagliazucchi L, Moschella MG, Guerrini R, Pacifico S, Luciani R, Genovese F, Henrich S, Alboni S, Santarem N, da Silva Cordeiro A, Giovannetti E, Peters GJ, Pinton P, Rimessi A, Cruciani G, Stroud RM, Wade RC, Mangani S, Marverti G, D'Arca D, Ponterini G, Costi MP. Costantino L, et al. Among authors: lauriola a. Elife. 2022 Dec 7;11:e73862. doi: 10.7554/eLife.73862. Elife. 2022. PMID: 36475542 Free PMC article.
Folic Acid-Peptide Conjugates Combine Selective Cancer Cell Internalization with Thymidylate Synthase Dimer Interface Targeting.
Marverti G, Marraccini C, Martello A, D'Arca D, Pacifico S, Guerrini R, Spyrakis F, Gozzi G, Lauriola A, Santucci M, Cannazza G, Tagliazucchi L, Cazzato AS, Losi L, Ferrari S, Ponterini G, Costi MP. Marverti G, et al. Among authors: lauriola a. J Med Chem. 2021 Mar 25;64(6):3204-3221. doi: 10.1021/acs.jmedchem.0c02107. Epub 2021 Mar 12. J Med Chem. 2021. PMID: 33710891 Free PMC article.
22 results