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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2010 2
2011 4
2012 5
2013 4
2014 5
2015 4
2016 5
2017 6
2018 5
2019 9
2020 6
2021 4
2022 5
2023 1
2024 0

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57 results

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Page 1
PROTAC-Induced Glycogen Synthase Kinase 3β Degradation as a Potential Therapeutic Strategy for Alzheimer's Disease.
Guardigni M, Pruccoli L, Santini A, Simone A, Bersani M, Spyrakis F, Frabetti F, Uliassi E, Andrisano V, Pagliarani B, Fernández-Gómez P, Palomo V, Bolognesi ML, Tarozzi A, Milelli A. Guardigni M, et al. Among authors: simone a. ACS Chem Neurosci. 2023 Jun 7;14(11):1963-1970. doi: 10.1021/acschemneuro.3c00096. Epub 2023 May 23. ACS Chem Neurosci. 2023. PMID: 37218653 Free PMC article.
Aβ1-42 peptide toxicity on neuronal cells: A lipidomic study.
Davani L, Fu X, De Simone A, Li P, Montanari S, Lämmerhofer M, Andrisano V. Davani L, et al. Among authors: de simone a. J Pharm Biomed Anal. 2022 Sep 20;219:114876. doi: 10.1016/j.jpba.2022.114876. Epub 2022 Jun 6. J Pharm Biomed Anal. 2022. PMID: 35749963
Multi-target neuroprotective effects of herbal medicines for Alzheimer's disease.
Fernandes F, Barroso MF, De Simone A, Emriková E, Dias-Teixeira M, Pereira JP, Chlebek J, Fernandes VC, Rodrigues F, Andrisano V, Delerue-Matos C, Grosso C. Fernandes F, et al. Among authors: de simone a. J Ethnopharmacol. 2022 May 23;290:115107. doi: 10.1016/j.jep.2022.115107. Epub 2022 Feb 14. J Ethnopharmacol. 2022. PMID: 35176467
From virtual screening hits targeting a cryptic pocket in BACE-1 to a nontoxic brain permeable multitarget anti-Alzheimer lead with disease-modifying and cognition-enhancing effects.
Pont C, Ginex T, Griñán-Ferré C, Scheiner M, Mattellone A, Martínez N, Arce EM, Soriano-Fernández Y, Naldi M, De Simone A, Barenys M, Gómez-Catalán J, Pérez B, Sabate R, Andrisano V, Loza MI, Brea J, Bartolini M, Bolognesi ML, Decker M, Pallàs M, Luque FJ, Muñoz-Torrero D. Pont C, et al. Among authors: de simone a. Eur J Med Chem. 2021 Dec 5;225:113779. doi: 10.1016/j.ejmech.2021.113779. Epub 2021 Aug 16. Eur J Med Chem. 2021. PMID: 34418785 Free article.
(±)-BIGI-3h: Pentatarget-Directed Ligand combining Cholinesterase, Monoamine Oxidase, and Glycogen Synthase Kinase 3β Inhibition with Calcium Channel Antagonism and Antiaggregating Properties for Alzheimer's Disease.
Ismaili L, Monnin J, Etievant A, Arribas RL, Viejo L, Refouvelet B, Soukup O, Janockova J, Hepnarova V, Korabecny J, Kucera T, Jun D, Andrys R, Musilek K, Baguet A, García-Frutos EM, De Simone A, Andrisano V, Bartolini M, de Los Ríos C, Marco-Contelles J, Haffen E. Ismaili L, et al. Among authors: de simone a. ACS Chem Neurosci. 2021 Apr 21;12(8):1328-1342. doi: 10.1021/acschemneuro.0c00803. Epub 2021 Apr 2. ACS Chem Neurosci. 2021. PMID: 33797877
Discovery of a Potent Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase with Antioxidant Activity that Alleviates Alzheimer-like Pathology in Old APP/PS1 Mice.
Viayna E, Coquelle N, Cieslikiewicz-Bouet M, Cisternas P, Oliva CA, Sánchez-López E, Ettcheto M, Bartolini M, De Simone A, Ricchini M, Rendina M, Pons M, Firuzi O, Pérez B, Saso L, Andrisano V, Nachon F, Brazzolotto X, García ML, Camins A, Silman I, Jean L, Inestrosa NC, Colletier JP, Renard PY, Muñoz-Torrero D. Viayna E, et al. Among authors: de simone a. J Med Chem. 2021 Jan 14;64(1):812-839. doi: 10.1021/acs.jmedchem.0c01775. Epub 2020 Dec 28. J Med Chem. 2021. PMID: 33356266
57 results